| Literature DB >> 27464074 |
Ming Yu, Ziqiang Wang, Min Lv, Rongzhang Hao1, Rongtao Zhao1, Lihua Qi1, Shima Liu, Chuhong Yu, Bowu Zhang, Chunhai Fan, Jingye Li.
Abstract
Multidrug-resistant superbugs are currently a severe threat to public health. Here, we report a novel kind of antisuperbug material prepared by irradiation induced graft polymerization of 1-butyl-3-vinyl imidazole chloride onto cotton fabric. The reduction of superbugs on this fabric is higher than 99.9%. Attributed to the strong covalent bonding between the graft chains and the cellulose macromolecules, the antisuperbug performance did not decrease even after 150 equiv of domestic laundering cycles. Covalent bonding also prevented the release of the antibacterial groups during application and guarantees the safety of the material, which was proved by animal skin irritation and acute oral toxicity tests.Entities:
Keywords: antibiotic resistance; antisuperbug cotton fabric; covalent bonding; laundering durability; radiation induced graft polymerization
Year: 2016 PMID: 27464074 DOI: 10.1021/acsami.6b07631
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN: 1944-8244 Impact factor: 9.229