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Literature DB >> 27461987

Metal-Organic-Framework-Derived Mesoporous Carbon Nanospheres Containing Porphyrin-Like Metal Centers for Conformal Phototherapy.

Shunhao Wang^1,2,3,4, Lu Shang², Linlin Li⁵, Yingjie Yu⁶, Chongwei Chi⁷, Kun Wang⁷, Jie Zhang^3,4, Run Shi^2,4, Heyun Shen¹, Geoffrey I N Waterhouse⁸, Sijin Liu⁹, Jie Tian⁷, Tierui Zhang¹⁰, Huiyu Liu¹¹.

Abstract

Mesoporous carbon nanospheres containing porphyrin-like metal centers (denoted as "PMCS") are successfully synthesized by the pyrolysis of an imidazolate framework using a mesoporous-silica protection strategy. The PMCS allow infrared and photoacoustic imaging and synergetic photothermal therapy/photodynamic therapy derived from the porphyrin-like moieties, offering the possibility of real-time monitoring of therapeutic processes and image-guided precise conformal phototherapy. PMCS thus represent a novel multifunctional theranostic platform for improved treatment efficiencies.

Entities: Chemical

Keywords: mesoporous carbon nanoframes; photodynamic therapy; photothermal therapy; porphyrin-like metal centers; reactive oxygen species

Mesh：

Substances：
Metals
Porphyrins
Carbon

Year: 2016 PMID： 27461987 DOI： 10.1002/adma.201602197

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

Keyword Cloud
Cited

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