Literature DB >> 27461202

Systemic Corticosteroids for the Prevention of Bronchopulmonary Dysplasia: Picking the Right Drug for the Right Baby.

Sara E Rostas1, Christopher McPherson.   

Abstract

Bronchopulmonary dysplasia is a morbidity of prematurity with implications into adulthood on respiratory and neurologic health. Multiple risk factors contribute to the development of bronchopulmonary dysplasia leading to examination of various strategies of prevention. Systemic corticosteroids are one prevention strategy with a large body of data, creating an ongoing controversy regarding the risks and benefits of therapy. Careful consideration of the available data along with the clinical characteristics of the individual infant is required before using this powerful therapy.

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Year:  2016        PMID: 27461202     DOI: 10.1891/0730-0832.35.4.234

Source DB:  PubMed          Journal:  Neonatal Netw        ISSN: 0730-0832


  2 in total

1.  Caffeine modulates glucocorticoid-induced expression of CTGF in lung epithelial cells and fibroblasts.

Authors:  Markus Fehrholz; Kirsten Glaser; Christian P Speer; Silvia Seidenspinner; Barbara Ottensmeier; Steffen Kunzmann
Journal:  Respir Res       Date:  2017-03-23

2.  Increase in CTGF mRNA expression by respiratory syncytial virus infection is abrogated by caffeine in lung epithelial cells.

Authors:  Steffen Kunzmann; Christine Krempl; Silvia Seidenspinner; Kirsten Glaser; Christian P Speer; Markus Fehrholz
Journal:  Influenza Other Respir Viruses       Date:  2018-05-22       Impact factor: 4.380

  2 in total

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