Literature DB >> 27459067

The Dynamics of Apoptotic Cell Clearance.

Michael R Elliott1, Kodi S Ravichandran2.   

Abstract

The phagocytic clearance of dying cells in a tissue is a highly orchestrated series of intercellular events coordinated by a complex signaling network. Recent data from genetic, biochemical, and live-imaging approaches have greatly enhanced our understanding of the dynamics of cell clearance and how the process is orchestrated at the cellular and tissue levels. We discuss how networks regulating apoptotic cell clearance are integrated to enable a rapid, efficient, and high-capacity clearance system within tissues.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  apoptosis; chemotaxis; efferocytosis; imaging; immunity; phagocytosis; signal transduction

Mesh:

Year:  2016        PMID: 27459067      PMCID: PMC4966906          DOI: 10.1016/j.devcel.2016.06.029

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  171 in total

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5.  Identification of a factor that links apoptotic cells to phagocytes.

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Journal:  Nature       Date:  2002-05-09       Impact factor: 49.962

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7.  The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.

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Journal:  J Cell Sci       Date:  2007-05-01       Impact factor: 5.285

8.  CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3).

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9.  Unexpected link between an antibiotic, pannexin channels and apoptosis.

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Journal:  Nature       Date:  2014-03-12       Impact factor: 49.962

10.  Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.

Authors:  Kristin Westphalen; Galina A Gusarova; Mohammad N Islam; Manikandan Subramanian; Taylor S Cohen; Alice S Prince; Jahar Bhattacharya
Journal:  Nature       Date:  2014-01-19       Impact factor: 49.962

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  108 in total

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Review 2.  Resolution of Crohn's disease.

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Journal:  Semin Immunopathol       Date:  2019-09-24       Impact factor: 9.623

Review 3.  Phosphatidylserine Is the Signal for TAM Receptors and Their Ligands.

Authors:  Greg Lemke
Journal:  Trends Biochem Sci       Date:  2017-07-19       Impact factor: 13.807

4.  Dying Neurons Utilize Innate Immune Signaling to Prime Glia for Phagocytosis during Development.

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Journal:  Dev Cell       Date:  2019-02-07       Impact factor: 12.270

5.  Cooperative epithelial phagocytosis enables error correction in the early embryo.

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Journal:  Nature       Date:  2021-02-10       Impact factor: 49.962

6.  Rab17 mediates intermixing of phagocytosed apoptotic cells with recycling endosomes.

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Journal:  Small GTPases       Date:  2017-05-04

7.  Binucleate germ cells in Caenorhabditis elegans are removed by physiological apoptosis.

Authors:  Stephan A Raiders; Michael D Eastwood; Meghan Bacher; James R Priess
Journal:  PLoS Genet       Date:  2018-07-19       Impact factor: 5.917

Review 8.  Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology.

Authors:  Sho Morioka; Christian Maueröder; Kodi S Ravichandran
Journal:  Immunity       Date:  2019-05-21       Impact factor: 31.745

9.  Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors.

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10.  Cutting Edge: STAT1-Mediated Epigenetic Control of Rsad2 Promotes Clonal Expansion of Antiviral NK Cells.

Authors:  Gabriela M Wiedemann; Clair D Geary; Colleen M Lau; Joseph C Sun
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