Literature DB >> 274587

Thirteen cases of leukemia in a family.

F W Gunz, J P Gunz, P C Vincent, M Bergin, F L Johnson, H Bashir, R L Kirk.   

Abstract

Thirteen cases of leukemia, 12 of them acute, occurred in 3 generations of a family comprising 293 members. Individual cases could not be linked to the possession of any of a range of genetic markers. Cytogenetic studies showed no constitutional chromosome abnormalities. Preliminary results of virologic studies suggested the presence of oncornaviruses in at least 1 leukemic individual in this family. This aggregation of leukemia cases likely resulted from a genetic, probably polygenic, predisposition, in association with the activity of leukemogenic factors whose nature remains to be clearly defined.

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Year:  1978        PMID： 274587     DOI： 10.1093/jnci/60.6.1243

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  5 in total

1.  Anticipation in familial leukemia.

Authors:  M Horwitz; E L Goode; G P Jarvik
Journal:  Am J Hum Genet       Date:  1996-11       Impact factor: 11.025

2.  Genetic heterogeneity in familial acute myelogenous leukemia: evidence for a second locus at chromosome 16q21-23.2.

Authors:  M Horwitz; K F Benson; F Q Li; J Wolff; M F Leppert; L Hobson; M Mangelsdorf; S Yu; D Hewett; R I Richards; W H Raskind
Journal:  Am J Hum Genet       Date:  1997-10       Impact factor: 11.025

3.  Malignant tumors during the first 2 decades of life in the offspring of atomic bomb survivors.

Authors:  Y Yoshimoto; J V Neel; W J Schull; H Kato; M Soda; R Eto; K Mabuchi
Journal:  Am J Hum Genet       Date:  1990-06       Impact factor: 11.025

4.  Familial history of cancer and childhood acute leukemia: a French population-based case-control study.

Authors:  Mahaut Ripert; Florence Menegaux; Yves Perel; Françoise Méchinaud; Emmanuel Plouvier; Virginie Gandemer; Patrick Lutz; Jean-Pierre Vannier; Jean-Pierre Lamagnére; Geneviève Margueritte; Patrick Boutard; Alain Robert; Corinne Armari-Alla; Martine Munzer; Frédéric Millot; Lionel de Lumley; Christian Berthou; Xavier Rialland; Brigitte Pautard; Jacqueline Clavel
Journal:  Eur J Cancer Prev       Date:  2007-10       Impact factor: 2.497

Review 5.  Acute Myeloid Leukemia With CEBPA Mutations: Current Progress and Future Directions.

Authors:  Long Su; Yuan-Yuan Shi; Zeng-Yan Liu; Su-Jun Gao
Journal:  Front Oncol       Date:  2022-02-01       Impact factor: 6.244
  5 in total

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