Literature DB >> 27458106

Depression and anxiety in patients receiving interferon-alpha: The role of illness perceptions.

Nilay Hepgul1, Carmine M Pariante1, Sara Baraldi1, Alessandra Borsini1, Chiara Bufalino1, Alice Russell1, Kosh Agarwal2, Anthony J Cleare1, Daniel M Forton3, Max Henderson1,2, Valeria Mondelli1, Gopinath Ranjith4, Matthew Hotopf1.   

Abstract

Development of psychiatric symptoms during interferon-alpha therapy may be influenced by psychological factors. We examined illness perceptions using the Revised Illness Perceptions Questionnaire in 55 patients with chronic hepatitis C virus infection, due to receive interferon-alpha. The Hospital Anxiety and Depression Scale was used to assess the development of symptoms. Negative identity, consequences and emotional representation beliefs were significantly associated with both higher depression and anxiety scores. Negative illness perceptions play a predictive role in the development of interferon-alpha-induced psychiatric symptoms.

Entities:  

Keywords:  anxiety; depression; illness perceptions; mood; psychological distress; side effects

Mesh:

Substances:

Year:  2016        PMID: 27458106     DOI: 10.1177/1359105316658967

Source DB:  PubMed          Journal:  J Health Psychol        ISSN: 1359-1053


  4 in total

Review 1.  Diet and depression: exploring the biological mechanisms of action.

Authors:  Wolfgang Marx; Melissa Lane; Meghan Hockey; Hajara Aslam; Michael Berk; Ken Walder; Alessandra Borsini; Joseph Firth; Carmine M Pariante; Kirsten Berding; John F Cryan; Gerard Clarke; Jeffrey M Craig; Kuan-Pin Su; David Mischoulon; Fernando Gomez-Pinilla; Jane A Foster; Patrice D Cani; Sandrine Thuret; Heidi M Staudacher; Almudena Sánchez-Villegas; Husnain Arshad; Tasnime Akbaraly; Adrienne O'Neil; Toby Segasby; Felice N Jacka
Journal:  Mol Psychiatry       Date:  2020-11-03       Impact factor: 15.992

2.  Interferon-Alpha Reduces Human Hippocampal Neurogenesis and Increases Apoptosis via Activation of Distinct STAT1-Dependent Mechanisms.

Authors:  Alessandra Borsini; Annamaria Cattaneo; Chiara Malpighi; Sandrine Thuret; Neil A Harrison; Patricia A Zunszain; Carmine M Pariante
Journal:  Int J Neuropsychopharmacol       Date:  2018-02-01       Impact factor: 5.176

3.  Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of chronic fatigue syndrome.

Authors:  Alice Russell; Nilay Hepgul; Naghmeh Nikkheslat; Alessandra Borsini; Zuzanna Zajkowska; Natalie Moll; Daniel Forton; Kosh Agarwal; Trudie Chalder; Valeria Mondelli; Matthew Hotopf; Anthony Cleare; Gabrielle Murphy; Graham Foster; Terry Wong; Gregor A Schütze; Markus J Schwarz; Neil Harrison; Patricia A Zunszain; Carmine M Pariante
Journal:  Psychoneuroendocrinology       Date:  2018-12-17       Impact factor: 4.905

4.  Intracerebroventricular Administration of Interferon-Alpha Induced Depressive-Like Behaviors and Neurotransmitter Changes in Rhesus Monkeys.

Authors:  Zhifei Li; Zhaoxia Li; Xiaoman Lv; Zhaofu Li; Lei Xiong; Xintian Hu; Dongdong Qin
Journal:  Front Neurosci       Date:  2020-11-19       Impact factor: 4.677

  4 in total

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