| Literature DB >> 27457283 |
Amr Hosny Malash1, Aliaa Adel Ali2, Rania Mohamed Samy3, Radwa Ahmed Shamma4.
Abstract
BACKGROUND: Bronchopulmonary dysplasia (BPD) remains a leading cause of morbidity and mortality during infancy. Evidence suggests that the Toll-like receptor (TLR) signaling pathway plays an integral role in lung inflammation and injury. This study aimed to detect single nucleotide polymorphisms (SNPs) in TLR pathway genes [TLR5 and Toll-interleukin 1 receptor domain-containing adaptor protein (TIRAP)] among preterm neonates and to determine their association with the development and severity of bronchopulmonary dysplasia.Entities:
Keywords: Bronchopulmonary dysplasia; Neonatal mortality; Oxygen therapy; Preterm neonates; Sepsis; Toll-like receptors
Mesh：
Substances：
Year: 2016 PMID： 27457283 DOI： 10.1016/j.gene.2016.07.049
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688