Literature DB >> 27457155

Targeting the Dark Horse of complement: the first generation of functionally selective C5aR2 ligands.

Claudia Kemper1,2.   

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Year:  2016        PMID： 27457155     DOI： 10.1038/icb.2016.62

Source DB:  PubMed          Journal:  Immunol Cell Biol        ISSN： 0818-9641            Impact factor:   5.126


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  9 in total

1.  Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.

Authors:  Daniel E Croker; Peter N Monk; Reena Halai; Geraldine Kaeslin; Zoe Schofield; Mike Cl Wu; Richard J Clark; Mark At Blaskovich; Dimitrios Morikis; Christodoulos A Floudas; Matthew A Cooper; Trent M Woodruff
Journal:  Immunol Cell Biol       Date:  2016-04-25       Impact factor: 5.126

Review 2.  IL-6 as a keystone cytokine in health and disease.

Authors:  Christopher A Hunter; Simon A Jones
Journal:  Nat Immunol       Date:  2015-05       Impact factor: 25.606

3.  The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74).

Authors:  Stuart A Cain; Peter N Monk
Journal:  J Biol Chem       Date:  2001-12-31       Impact factor: 5.157

4.  Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis.

Authors:  Peter N Lalli; Michael G Strainic; Min Yang; Feng Lin; M Edward Medof; Peter S Heeger
Journal:  Blood       Date:  2008-06-20       Impact factor: 22.113

5.  The chemotactic receptor for human C5a anaphylatoxin.

Authors:  N P Gerard; C Gerard
Journal:  Nature       Date:  1991-02-14       Impact factor: 49.962

6.  C5a-stimulated recruitment of beta-arrestin2 to the nonsignaling 7-transmembrane decoy receptor C5L2.

Authors:  Lambertus H C Van Lith; Julia Oosterom; Andrea Van Elsas; Guido J R Zaman
Journal:  J Biomol Screen       Date:  2009-07-29

Review 7.  Function, structure and therapeutic potential of complement C5a receptors.

Authors:  P N Monk; A-M Scola; P Madala; D P Fairlie
Journal:  Br J Pharmacol       Date:  2007-07-02       Impact factor: 8.739

8.  Derivation of ligands for the complement C3a receptor from the C-terminus of C5a.

Authors:  Reena Halai; Meghan L Bellows-Peterson; Will Branchett; James Smadbeck; Chris A Kieslich; Daniel E Croker; Matthew A Cooper; Dimitrios Morikis; Trent M Woodruff; Christodoulos A Floudas; Peter N Monk
Journal:  Eur J Pharmacol       Date:  2014-10-30       Impact factor: 4.432

Review 9.  Complement--tapping into new sites and effector systems.

Authors:  Martin Kolev; Gaelle Le Friec; Claudia Kemper
Journal:  Nat Rev Immunol       Date:  2014-11-14       Impact factor: 53.106
  9 in total
  2 in total

1.  Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2.

Authors:  Christian M Karsten; Tina Beckmann; Maike M Holtsche; Jenny Tillmann; Sabrina Tofern; Franziska S Schulze; Eva Nina Heppe; Ralf J Ludwig; Detlef Zillikens; Inke R König; Jörg Köhl; Enno Schmidt
Journal:  Front Immunol       Date:  2018-03-15       Impact factor: 7.561

2.  Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects.

Authors:  Mieke C Louwe; Trine Ranheim; Margrethe Holt; Bjørn E Seim; Jonas Øgaard; Maria B Olsen; Per R Woldbæk; J P Kvitting; Pål Aukrust; Arne Yndestad; Tom Eirik Mollnes; Per H Nilsson
Journal:  Open Heart       Date:  2019-11-10
  2 in total

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