Literature DB >> 2745715

Monoclonal antibody based immunoassay for human aminoacylase-1.

Y E Miller1, B Kao.   

Abstract

Aminoacylase-1 is expressed in a wide variety of cell types. Although the exact role of this enzyme in cellular physiology remains unclear, it has been postulated to function in the salvage of acylated aminoacids. The enzyme is also of interest due to its gene map location on chromosome 3p21, a region deleted in several neoplasms. We have produced mouse monoclonal antibodies and rabbit antisera which recognize human aminoacylase-1. A sandwich ELISA has been developed which allows the measurement of human aminoacylase-1.

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Year:  1989        PMID: 2745715     DOI: 10.1080/01971528908053232

Source DB:  PubMed          Journal:  J Immunoassay        ISSN: 0197-1522


  3 in total

1.  Aminoacylase I from porcine kidney: identification and characterization of two major protein domains.

Authors:  G J Palm; K H Röhm
Journal:  J Protein Chem       Date:  1995-05

2.  Dissecting the pretransitional conformational changes in aminoacylase I thermal denaturation.

Authors:  Jing-Tan Su; Sung-Hye Kim; Yong-Bin Yan
Journal:  Biophys J       Date:  2006-10-27       Impact factor: 4.033

3.  Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation.

Authors:  Matthew P Welberry Smith; Alexandre Zougman; David A Cairns; Michelle Wilson; Tobias Wind; Steven L Wood; Douglas Thompson; Michael P Messenger; Andrew Mooney; Peter J Selby; Andrew J P Lewington; Rosamonde E Banks
Journal:  Kidney Int       Date:  2013-06-05       Impact factor: 10.612

  3 in total

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