Literature DB >> 2745591

A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden.

S Steffenburg1, C Gillberg, L Hellgren, L Andersson, I C Gillberg, G Jakobsson, M Bohman.   

Abstract

The Nordic countries were screened for the occurrence of cases of autism with a same-sexed twin under age 25 years. Twenty-one pairs (11 monozygotic and 10 dizygotic) of twins and one set of identical triplets were found and extensively examined. The concordance for autism by pair was 91% in the monoygotic and 0% in the dizygotic pairs. The corresponding concordances for cognitive disorder were 91% and 30%, respectively. In most of the pairs discordant for autism, the autistic twin had more perinatal stress. The results lend support for the notion that autism sometimes has a hereditary component and that perinatal stress is involved in some cases.

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Mesh：

Year:  1989        PMID： 2745591     DOI： 10.1111/j.1469-7610.1989.tb00254.x

Source DB:  PubMed          Journal:  J Child Psychol Psychiatry        ISSN： 0021-9630            Impact factor:   8.982


  237 in total

1.  A genomic screen of autism: evidence for a multilocus etiology.

Authors:  N Risch; D Spiker; L Lotspeich; N Nouri; D Hinds; J Hallmayer; L Kalaydjieva; P McCague; S Dimiceli; T Pitts; L Nguyen; J Yang; C Harper; D Thorpe; S Vermeer; H Young; J Hebert; A Lin; J Ferguson; C Chiotti; S Wiese-Slater; T Rogers; B Salmon; P Nicholas; P B Petersen; C Pingree; W McMahon; D L Wong; L L Cavalli-Sforza; H C Kraemer; R M Myers
Journal:  Am J Hum Genet       Date:  1999-08       Impact factor: 11.025

2.  Brief report: autism and Asperger syndrome in seven-year-old children: a total population study.

Authors:  B Kadesjö; C Gillberg; B Hagberg
Journal:  J Autism Dev Disord       Date:  1999-08

Review 3.  Genetic studies of autism: from the 1970s into the millennium.

Authors:  M Rutter
Journal:  J Abnorm Child Psychol       Date:  2000-02

4.  Exclusion of linkage to the HLA region in ninety multiplex sibships with autism.

Authors:  T Rogers; L Kalaydjieva; J Hallmayer; P B Petersen; P Nicholas; C Pingree; W M McMahon; D Spiker; L Lotspeich; H Kraemer; P McCague; S Dimiceli; N Nouri; T Peachy; J Yang; D Hinds; N Risch; R M Myers
Journal:  J Autism Dev Disord       Date:  1999-06

Review 5.  Heterogeneity and the genetics of autism.

Authors:  P Szatmari
Journal:  J Psychiatry Neurosci       Date:  1999-03       Impact factor: 6.186

6.  Excess of twins among affected sibling pairs with autism: implications for the etiology of autism.

Authors:  D A Greenberg; S E Hodge; J Sowinski; D Nicoll
Journal:  Am J Hum Genet       Date:  2001-10-02       Impact factor: 11.025

7.  Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity.

Authors:  J D Buxbaum; J M Silverman; C J Smith; M Kilifarski; J Reichert; E Hollander; B A Lawlor; M Fitzgerald; D A Greenberg; K L Davis
Journal:  Am J Hum Genet       Date:  2001-05-14       Impact factor: 11.025

Review 8.  Autism: current theories regarding its pathogenesis and implications for rational pharmacotherapy.

Authors:  J K Buitelaar; S H Willemsen-Swinkels
Journal:  Paediatr Drugs       Date:  2000 Jan-Feb       Impact factor: 3.022

Review 9.  Assessment in multisite randomized clinical trials of patients with autistic disorder: the Autism RUPP Network. Research Units on Pediatric Psychopharmacology.

Authors:  L E Arnold; M G Aman; A Martin; A Collier-Crespin; B Vitiello; E Tierney; R Asarnow; F Bell-Bradshaw; B J Freeman; P Gates-Ulanet; A Klin; J T McCracken; C J McDougle; J J McGough; D J Posey; L Scahill; N B Swiezy; L Ritz; F Volkmar
Journal:  J Autism Dev Disord       Date:  2000-04

Review 10.  Autism: in search of susceptibility genes.

Authors:  Janine A Lamb; Jeremy R Parr; Anthony J Bailey; Anthony P Monaco
Journal:  Neuromolecular Med       Date:  2002       Impact factor: 3.843
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