Christian B Laursen1, Therese M H Naur, Uffe Bodtger, Sara Colella, Matiullah Naqibullah, Valentina Minddal, Lars Konge, Jesper R Davidsen, Niels-Christian Hansen, Ole Graumann, Paul F Clementsen. 1. *Department of Respiratory Medicine †Centre for Thoracic Oncology, Odense University Hospital ‡Institute for Clinical Research #Institute for Regional Health Research, University of Southern Denmark, Odense C §Department of Respiratory Medicine, Gentofte University Hospital, Hellerup ∥Copenhagen Academy for Medical Simulation and Simulation (CAMES), University of Copenhagen and the Capital Region of Denmark, Copenhagen ¶Department of Respiratory and Internal Medicine, Næstved Hospital, Næstved **Radiology Department, Aarhus University Hospital, Aarhus N ††Center of Clinical Ultrasound (CECLUS), Aarhus University, Aarhus C, Denmark.
Abstract
BACKGROUND: The aim of the study was to determine the diagnostic yield and prevalence of complications of ultrasound-guided transthoracic needle aspiration biopsies (US-TTNAB) performed by respiratory physicians after implementation of the procedure in an everyday clinical setting at 3 different centers. METHODS: Patients were included if they during the period from January 2012 to August 2014 had a registered US-TTNAB procedure code or if a US biopsy registration form had been filled out at either of the participating centers. Histology or cytology results were used as a reference test for diagnoses that could be made based on these results. Reference test for the remaining diagnoses was clinical follow-up. The diagnostic yield of US-TTNAB was defined as the proportion of patients in which the result of the US-TTNAB was consistent with the reference test. RESULTS: A total of 215 patients in which a primary US-TTNAB had been performed were identified. The most common biopsy sites were lungs and pleurae with a total of 164 (76.3%) patients and 31 patients (14.4%), respectively. US-TTNAB diagnostic yield was 76.9% (95% CI, 70.3%-83.4%) for malignant diagnoses and 47.6% (95% CI, 31.9%-63.4%) for nonmalignant diagnoses. The most common complications of US-TTNAB were pneumothorax (2.5%; 95% CI, 0.03%-4.6%) and pain at the biopsy site (2%; 95% CI, 0.04%-3.9%). No fatalities related to US-TTNAB were observed. CONCLUSION: US-TTNAB performed by respiratory physicians is a safe procedure with a low risk of complications and the diagnostic yield to establish a malignant diagnosis is acceptable.
BACKGROUND: The aim of the study was to determine the diagnostic yield and prevalence of complications of ultrasound-guided transthoracic needle aspiration biopsies (US-TTNAB) performed by respiratory physicians after implementation of the procedure in an everyday clinical setting at 3 different centers. METHODS:Patients were included if they during the period from January 2012 to August 2014 had a registered US-TTNAB procedure code or if a US biopsy registration form had been filled out at either of the participating centers. Histology or cytology results were used as a reference test for diagnoses that could be made based on these results. Reference test for the remaining diagnoses was clinical follow-up. The diagnostic yield of US-TTNAB was defined as the proportion of patients in which the result of the US-TTNAB was consistent with the reference test. RESULTS: A total of 215 patients in which a primary US-TTNAB had been performed were identified. The most common biopsy sites were lungs and pleurae with a total of 164 (76.3%) patients and 31 patients (14.4%), respectively. US-TTNAB diagnostic yield was 76.9% (95% CI, 70.3%-83.4%) for malignant diagnoses and 47.6% (95% CI, 31.9%-63.4%) for nonmalignant diagnoses. The most common complications of US-TTNAB were pneumothorax (2.5%; 95% CI, 0.03%-4.6%) and pain at the biopsy site (2%; 95% CI, 0.04%-3.9%). No fatalities related to US-TTNAB were observed. CONCLUSION: US-TTNAB performed by respiratory physicians is a safe procedure with a low risk of complications and the diagnostic yield to establish a malignant diagnosis is acceptable.
Authors: Michael Offin; Jacob J Chabon; Pedram Razavi; James M Isbell; Charles M Rudin; Maximilian Diehn; Bob T Li Journal: J Oncol Date: 2017-03-14 Impact factor: 4.375
Authors: Julia d'Hooghe; Haizea Alvarez Martinez; Pia Iben Pietersen; Christian B Laursen; Nicole Hersch; Ádám Domonkos Tárnoki; Simon Walsh; Jouke Annema; Daniela Gompelmann Journal: ERJ Open Res Date: 2020-07-20