Literature DB >> 27452927

Construction of Optically Active Isotwistanes and Aminocyclitols Using Chiral Cyclohexadiene as a Common Intermediate.

Shinji Harada1, Kexin Li, Ryuto Kino, Takuya Takeda, Chia-Hsien Wu, Shiharu Hiraoka, Atsushi Nishida.   

Abstract

We have developed a new method for synthesizing chiral isotwistane and homoisotwistane skeletons as well as aminocyclitols in a highly stereoselective manner. These results were achieved through the use of a common intermediate, which was derived from the ytterbium-catalyzed asymmetric Diels-Alder reaction of Danishefsky diene.

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Year:  2016        PMID: 27452927     DOI: 10.1248/cpb.c16-00431

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Pd-Catalyzed Cascade Reactions of Aziridines: One-Step Access to Complex Tetracyclic Amines.

Authors:  Jonathan P Knowles; Hannah G Steeds; Maria Schwarz; Francesca Latter; Kevin I Booker-Milburn
Journal:  Org Lett       Date:  2021-06-16       Impact factor: 6.005

  1 in total

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