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Literature DB >> 2745158

Lectin-binding studies of a human skin mastocytoma.

U Schumacher¹, H P Horny, U Welsch, E Kaiserling.

Abstract

A solitary mastocytoma of the skin was investigated to assess the lectin-binding pattern of human mast cells. Of 18 Fluorescein-labelled lectins tested, nine reacted with mast cell granules. While lectins recognizing N-acetylgalactosamine or fucose residues did not stain mast cells, lectins with binding sites for N-acetylglucosamine, alpha-methyl mannopyranoside, galactose, complex carbohydrates of N-acetyl-lactosamine type and sialic acid gave a positive reaction.

Entities: Chemical Disease Species

Mesh：

Substances：
Lectins

Year: 1989 PMID： 2745158 DOI： 10.1007/bf01002470

Source DB: PubMed Journal: Histochem J ISSN： 0018-2214

16 in total

1. Mast cell leukaemia: evidence for bone marrow origin of the pathological clone.

Authors: R Dalton; L Chan; E Batten; S Eridani
Journal: Br J Haematol Date: 1986-10 Impact factor: 6.998

2. Lectin histochemistry of the mast cell: a light microscopical study.

Authors: C J Kirkpatrick; C J Jones; R W Stoddart
Journal: Histochem J Date: 1988-03

Review 3. Lectin cytochemistry and histochemistry.

Authors: I Damjanov
Journal: Lab Invest Date: 1987-07 Impact factor: 5.662

4. The lectin leucoagglutinin binds specifically to human granulocytes, monocytes and tissue mast cells: further evidence for a common origin of the three cell types.

Authors: U Schumacher; H P Horny; U Welsch
Journal: Br J Haematol Date: 1987-07 Impact factor: 6.998

1. Glycosylation patterns of the human colon cancer cell line HT-29 detected by Helix pomatia agglutinin and other lectins in culture, in primary tumours and in metastases in SCID mice.

Authors: U Schumacher; E Adam; D J Flavell; D Boehm; S A Brooks; A J Leathem
Journal: Clin Exp Metastasis Date: 1994-11 Impact factor: 5.150

2. A dot blot technique for the analysis of interactions of lectins with glycosaminoglycans.

Authors: U Schumacher; E Thielke; E Adam
Journal: Histochem J Date: 1992-07

2 in total

Lectin-binding studies of a human skin mastocytoma.

1. Mast cell leukaemia: evidence for bone marrow origin of the pathological clone.

2. Lectin histochemistry of the mast cell: a light microscopical study.

Review 3. Lectin cytochemistry and histochemistry.

4. The lectin leucoagglutinin binds specifically to human granulocytes, monocytes and tissue mast cells: further evidence for a common origin of the three cell types.

Review 5. The lectins: carbohydrate-binding proteins of plants and animals.

6. Bone marrow findings in systemic mastocytosis.

7. Nonspecific staining of mast cells by avidin-biotin-peroxidase complexes (ABC).

8. Lectin receptors as markers of lymphoid cells. I. Demonstration in tissue section by peroxidase technique.

9. Glycosaminoglycans in rat mucosal mast cells.

10. Ultrastructural evidence for the common origin of human mast cells and basophils.

1. Glycosylation patterns of the human colon cancer cell line HT-29 detected by Helix pomatia agglutinin and other lectins in culture, in primary tumours and in metastases in SCID mice.

2. A dot blot technique for the analysis of interactions of lectins with glycosaminoglycans.