Literature DB >> 27450558

Indeterminate form of Chagas disease: is left ventricular torsional mechanics a clue to subclinical myocardial abnormalities?

Marcio Silva Miguel Lima1, Mariana Callil Voos2, Wilson Mathias2, Jeane Mike Tsutsui2.   

Abstract

BACKGROUND: Chagas disease (CD) is highly endemic in Latin America, and has been emerging in developed countries. Early diagnosis of left ventricular (LV) systolic dysfunction, routinely done by echocardiography, is crucial for therapy. Speckle tracking echocardiography allows determination of LV segmental rotations, twist/torsion, and this analysis may disclose an unapparent myocardial contractile deficit in initial stages of CD. Therefore, this study aimed to highlight a possible unapparent myocardial contractile deficit in CD indeterminate form (IF) by a comprehensive torsional mechanics analysis.
METHODS: Patients with CDIF diagnosis, initial chagasic cardiomyopathy (CCMP characterized by ECG abnormalities and LVEF > 0.55), and normal controls were prospectively enrolled, and underwent conventional echocardiogram with images acquisition for STE offline analysis. Target parameters were basal and apical rotations, and calculation of twist and torsion.
RESULTS: A total of 42 patients were included (CDIF, eight; CCMP, 13; and 21 controls). Chagasic patients had a mean age of 55 years, five (24 %) men, and controls, 50 years, seven (33 %) men. Torsional mechanics analyzes resulted in no significant difference in all parameters studied between groups. Twist in CDIF was 20.8° ± 6.5°; CCMP, 19.0° ± 3.5° and controls, 19.7° ± 3.7° (p = 0.67). Torsion in CDIF was 2.6° ± 0.8°; CCMP, 2.4° ± 0.6° and controls, 2.4° ± 0.5° (p = 0.63).
CONCLUSIONS: Patients with Chagas disease have no abnormalities in torsional mechanics during its indeterminate and initial cardiomyopathy stages.

Entities:  

Keywords:  Chagas disease; Speckle tracking; Torsion; Twist

Mesh:

Year:  2016        PMID: 27450558     DOI: 10.1007/s12574-016-0305-5

Source DB:  PubMed          Journal:  J Echocardiogr        ISSN: 1349-0222


  24 in total

1.  [I Latin American guidelines for the diagnosis and treatment of Chagas cardiomyopathy].

Authors:  Jadelson Pinheiro de Andrade; José Antônio Marin-Neto; Angelo Amato Vincenzo de Paola; Fábio Vilas-Boas; Gláucia Maria Moraes Oliveira; Fernando Bacal; Edimar Alcides Bocchi; Dirceu Rodrigues Almeida; Abílio Augusto Fragata Filho; Maria da Consolação Vieira Moreira; Sérgio Salles Xavier; Wilson Alves de Oliveira Junior; João Carlos Pinto Dias
Journal:  Arq Bras Cardiol       Date:  2011       Impact factor: 2.000

2.  [Evaluation of segmentary contractility in Chagas' disease by using the integral of the myocardial velocity gradient (myocardial strain) obtained through tissue Doppler echocardiography].

Authors:  Carlos Eduardo Suaide Silva; Luiz Darcy Cortez Ferreira; Luciana Braz Peixoto; Claudia Gianini Monaco; Manuel Adán Gil; Juarez Ortiz; Bárbara Maria Ianni; José Lázaro Andrade; Wilson Mathias Júnior; Antônio Carlos Pereira Barretto
Journal:  Arq Bras Cardiol       Date:  2005-05-02       Impact factor: 2.000

Review 3.  Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endorsed by the Japanese Society of Echocardiography.

Authors:  Victor Mor-Avi; Roberto M Lang; Luigi P Badano; Marek Belohlavek; Nuno Miguel Cardim; Genevieve Derumeaux; Maurizio Galderisi; Thomas Marwick; Sherif F Nagueh; Partho P Sengupta; Rosa Sicari; Otto A Smiseth; Beverly Smulevitz; Masaaki Takeuchi; James D Thomas; Mani Vannan; Jens-Uwe Voigt; Jose Luis Zamorano
Journal:  Eur J Echocardiogr       Date:  2011-03

4.  Right ventricular endomyocardial biopsy in chronic Chagas' disease.

Authors:  A C Pereira Barretto; C Mady; E Arteaga-Fernandez; N Stolf; E A Lopes; M L Higuchi; G Bellotti; F Pileggi
Journal:  Am Heart J       Date:  1986-02       Impact factor: 4.749

5.  New noninvasive method for assessment of left ventricular rotation: speckle tracking echocardiography.

Authors:  Thomas Helle-Valle; Jonas Crosby; Thor Edvardsen; Erik Lyseggen; Brage H Amundsen; Hans-Jørgen Smith; Boaz D Rosen; João A C Lima; Hans Torp; Halfdan Ihlen; Otto A Smiseth
Journal:  Circulation       Date:  2005-11-15       Impact factor: 29.690

6.  Myocardial deformation analysis in Chagas heart disease with the use of speckle tracking echocardiography.

Authors:  Ana García-Álvarez; Marta Sitges; Ander Regueiro; Silvia Poyatos; Maria Jesus Pinazo; Elisabeth Posada; Bart Bijnens; Magda Heras; Joaquim Gascon; Ginés Sanz
Journal:  J Card Fail       Date:  2011-09-09       Impact factor: 5.712

Review 7.  Echocardiography in Chagas heart disease.

Authors:  Harry Acquatella
Journal:  Circulation       Date:  2007-03-06       Impact factor: 29.690

8.  Left ventricular global performance and diastolic function in indeterminate and cardiac forms of Chagas' disease.

Authors:  Antônio Pazin-Filho; Minna M Dias Romano; Rogério Gomes Furtado; Oswaldo César de Almeida Filho; André Schmidt; José Antonio Marin-Neto; Benedito Carlos Maciel
Journal:  J Am Soc Echocardiogr       Date:  2007-08-30       Impact factor: 5.251

9.  Chagas disease: a Latin American health problem becoming a world health problem.

Authors:  Gabriel A Schmunis; Zaida E Yadon
Journal:  Acta Trop       Date:  2009-11-20       Impact factor: 3.112

10.  Apical rotation by speckle tracking echocardiography: a simplified bedside index of left ventricular twist.

Authors:  Anders Opdahl; Thomas Helle-Valle; Espen W Remme; Trond Vartdal; Eirik Pettersen; Ketil Lunde; Thor Edvardsen; Otto A Smiseth
Journal:  J Am Soc Echocardiogr       Date:  2008-08-29       Impact factor: 5.251

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  2 in total

Review 1.  Longitudinal Speckle Tracking Strain Abnormalities in Chagas Disease: A Systematic Review and Meta-Analysis.

Authors:  Sergio Alejandro Gómez-Ochoa; Lyda Z Rojas; Juliana Alexandra Hernández-Vargas; Jorge Largo; Taulant Muka; Luis E Echeverría
Journal:  J Clin Med       Date:  2022-01-31       Impact factor: 4.241

2.  Prospective analysis of myocardial strain through the evolution of Chagas disease in the hamster animal model.

Authors:  Fernando Fonseca França Ribeiro; Henrique Turin Moreira; Antônio Carlos Leite de Barros-Filho; Denise M Tanaka; Camila G Fabricio; Luciano F L Oliveira; Cibele M Prado; Marcus V Simões; André Schmidt; Benedito C Maciel; José A Marin-Neto; Minna Moreira Dias Romano
Journal:  Int J Cardiovasc Imaging       Date:  2021-09-18       Impact factor: 2.357

  2 in total

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