Literature DB >> 27450439

β-catenin signalling in dermal papilla cells leads to a hairy situation.

Rita Gemayel1, Emily J Chenette1.   

Abstract

Dermal papilla (DP) are specialised mesenchymal cells that activate the formation of new hair follicles. In this issue of The FEBS Journal, Zhang and colleagues show that enhancing the β-catenin signalling pathway in DP cells allows faster and denser hair growth, providing a potential target for hair loss treatments and for improving hair regeneration techniques.
© 2016 Federation of European Biochemical Societies.

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Year:  2016        PMID: 27450439     DOI: 10.1111/febs.13799

Source DB:  PubMed          Journal:  FEBS J        ISSN: 1742-464X            Impact factor:   5.542


  2 in total

1.  HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro.

Authors:  Dongjie Sun; Zhehao Huang; Jinying Xu; Yiqing Wang; Lin Chen; Yi Hou; Guangfan Chi
Journal:  Mol Med Rep       Date:  2021-03-24       Impact factor: 2.952

Review 2.  Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy.

Authors:  Dimitri Papukashvili; Nino Rcheulishvili; Cong Liu; Fengfei Xie; Deependra Tyagi; Yunjiao He; Peng George Wang
Journal:  Cells       Date:  2021-10-30       Impact factor: 6.600

  2 in total

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