Edward Leinaar1, Arsham Alamian2, Liang Wang1. 1. Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City. 2. Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City. Electronic address: alamian@etsu.edu.
Abstract
PURPOSE: The association of asthma and overweight in youth is well studied. However, the temporal relationship between asthma and overweight, the strength of their association, and mediating factors involved in this relationship remain unclear. This review investigates the relationship between asthma and overweight in youth, while examining the role of physical activity as a mediator. METHODS: A systematic review of literature was conducted using PubMed and Medline databases. Studies conducted among youth aged 0-18 years, published in English between 2000-2014 were included. The Strengthening the Reporting of Observational Studies in Epidemiology guidelines were consulted to evaluate quality of selected citations. RESULTS: A comprehensive search yielded 143 studies in PubMed and 133 studies in Medline databases. Of these, 75 studies met the eligibility criteria. The review found varying hypotheses regarding the temporal relationship between asthma and overweight in youth; existing evidence supports the mediation of this association by decreased expenditure of energy due to reduced physical activity. Negative self-perception or parental perception of exercise ability due to asthma symptoms secondary to physical exertion was identified as a determinant of physical activity in asthmatic youth. CONCLUSIONS: Physical activity likely mediates the relationship between asthma and overweight in youth. Temporality of this relationship remains unclear.
PURPOSE: The association of asthma and overweight in youth is well studied. However, the temporal relationship between asthma and overweight, the strength of their association, and mediating factors involved in this relationship remain unclear. This review investigates the relationship between asthma and overweight in youth, while examining the role of physical activity as a mediator. METHODS: A systematic review of literature was conducted using PubMed and Medline databases. Studies conducted among youth aged 0-18 years, published in English between 2000-2014 were included. The Strengthening the Reporting of Observational Studies in Epidemiology guidelines were consulted to evaluate quality of selected citations. RESULTS: A comprehensive search yielded 143 studies in PubMed and 133 studies in Medline databases. Of these, 75 studies met the eligibility criteria. The review found varying hypotheses regarding the temporal relationship between asthma and overweight in youth; existing evidence supports the mediation of this association by decreased expenditure of energy due to reduced physical activity. Negative self-perception or parental perception of exercise ability due to asthma symptoms secondary to physical exertion was identified as a determinant of physical activity in asthmatic youth. CONCLUSIONS: Physical activity likely mediates the relationship between asthma and overweight in youth. Temporality of this relationship remains unclear.
Authors: Magnus Svartengren; Gui-Hong Cai; Andrei Malinovschi; Jenny Theorell-Haglöw; Christer Janson; Sölve Elmståhl; Lars Lind; Erik Lampa; Eva Lindberg Journal: ERJ Open Res Date: 2020-11-02
Authors: Jeong-Hui Park; Myong-Won Seo; Hyun Chul Jung; Jong-Kook Song; Jung-Min Lee Journal: Int J Environ Res Public Health Date: 2021-06-21 Impact factor: 3.390
Authors: Anna C Rivera; Teresa M Powell; Edward J Boyko; Rachel U Lee; Dennis J Faix; David D Luxton; Rudolph P Rull Journal: Am J Epidemiol Date: 2018-10-01 Impact factor: 4.897
Authors: Russell Jago; Ruth E Salway; Andy R Ness; Julian P Hamilton Shield; Matthew J Ridd; A John Henderson Journal: BMJ Open Date: 2019-01-20 Impact factor: 2.692