Literature DB >> 27449395

Systems pharmacology in drug development and therapeutic use - A forthcoming paradigm shift.

Charlotte Kloft1, Miriam N Trame2, Christoph A Ritter3.   

Abstract

Mesh：

Year:  2016        PMID： 27449395     DOI： 10.1016/j.ejps.2016.07.014

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN： 0928-0987            Impact factor:   4.384


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  7 in total

1.  Understanding and reducing complex systems pharmacology models based on a novel input-response index.

Authors:  Jane Knöchel; Charlotte Kloft; Wilhelm Huisinga
Journal:  J Pharmacokinet Pharmacodyn       Date:  2017-12-14       Impact factor: 2.745

2.  Exploiting Pharmacokinetic Models of Tamoxifen and Endoxifen to Identify Factors Causing Subtherapeutic Concentrations in Breast Cancer Patients.

Authors:  Lena Klopp-Schulze; Markus Joerger; Sebastian G Wicha; Rob Ter Heine; Chantal Csajka; Zinnia P Parra-Guillen; Charlotte Kloft
Journal:  Clin Pharmacokinet       Date:  2018-02       Impact factor: 6.447

3.  Network pharmacology exploration reveals the bioactive compounds and molecular mechanisms of Li-Ru-Kang against hyperplasia of mammary gland.

Authors:  Shizhang Wei; Xuelin Zhou; Ming Niu; Haizhu Zhang; Xiaoyi Liu; Ruilin Wang; Pengyan Li; Haotian Li; Huadan Cai; Yanling Zhao
Journal:  Mol Genet Genomics       Date:  2019-05-03       Impact factor: 3.291

Review 4.  The Role of Systems Biologic Approach in Cell Signaling and Drug Development Responses-A Mini Review.

Authors:  Vrushali Abhyankar; Paul Bland; Gabriela Fernandes
Journal:  Med Sci (Basel)       Date:  2018-05-30

5.  Protective Effect and Mechanism of Boswellic Acid and Myrrha Sesquiterpenes with Different Proportions of Compatibility on Neuroinflammation by LPS-Induced BV2 Cells Combined with Network Pharmacology.

Authors:  Xiao-Dong Miao; Li-Jie Zheng; Zi-Zhang Zhao; Shu-Lan Su; Yue Zhu; Jian-Ming Guo; Er-Xin Shang; Da-Wei Qian; Jin-Ao Duan
Journal:  Molecules       Date:  2019-10-31       Impact factor: 4.411

6.  System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus.

Authors:  Shi-Jun Yue; Juan Liu; Wu-Wen Feng; Fei-Long Zhang; Jian-Xin Chen; Lan-Ting Xin; Cheng Peng; Hua-Shi Guan; Chang-Yun Wang; Dan Yan
Journal:  Front Pharmacol       Date:  2017-10-05       Impact factor: 5.810

7.  A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice.

Authors:  Sebastian Franck; Robin Michelet; Fiordiligie Casilag; Jean-Claude Sirard; Sebastian G Wicha; Charlotte Kloft
Journal:  Pharmaceutics       Date:  2021-03-30       Impact factor: 6.321
  7 in total

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