| Literature DB >> 27448033 |
Jie Ma1, Xiu-Li Zhang1, Yu Wang1, Ji-Yong Zheng2, Chang-Yun Wang1,3, Chang-Lun Shao1,3.
Abstract
Two new flavones, aspergivones A (1) and B (2), were isolated from the fungus Aspergillus candidus cultured from the gorgonian coral Anthogorgia ochracea collected from the South China Sea. The structures of 1 and 2 were elucidated by NMR and MS methods and comparison with relatively known compounds. Only 2 showed slight inhibitory activity against alpha-glucosidase with an IC50 value of 244 μg/mL. Compounds 1 and 2 were also evaluated for their cytotoxic and antibacterial activities.Entities:
Keywords: Aspergillus candidus; alpha-glucosidase; flavone; gorgonian coral
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Year: 2016 PMID： 27448033 DOI： 10.1080/14786419.2016.1207073
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861