| Literature DB >> 2744764 |
N C Lan1, C Heinzmann, A Gal, I Klisak, U Orth, E Lai, J Grimsby, R S Sparkes, T Mohandas, J C Shih.
Abstract
Monoamine oxidase A and B (MAO A and B) are the central enzymes that catalyze oxidative deamination of biogenic amines throughout the body. The regional locations of genes encoding MAO A and B on the X chromosome were determined by using full-length cDNA clones for human MAO A and B, respectively. Using somatic cell hybrids, in situ hybridization, and field-inversion gel electrophoresis as well as deletion mapping in a patient with Norrie disease, we concluded that these two genes are close to each other and to the DXS7 locus (Xp 11.3).Entities:
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Year: 1989 PMID： 2744764 DOI： 10.1016/0888-7543(89)90279-6
Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736