| Literature DB >> 27447346 |
Rapeepat Sangsuwan1, Allie C Obermeyer, Phum Tachachartvanich, Krishnan K Palaniappan, Matthew B Francis.
Abstract
A convenient two-step method is described for the detection of nitrotyrosine-containing proteins. First, nitrotyrosines are reduced to aminophenols using sodium dithionite. Following this, an oxidative coupling reaction is used to attach anilines bearing fluorescence reporters or affinity probes. Features of this approach include fast reaction times, pmol-level sensitivity, and excellent chemoselectivity.Entities:
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Year: 2016 PMID: 27447346 PMCID: PMC5001876 DOI: 10.1039/c6cc04575h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222