Literature DB >> 27446576

Conformal 3D planned radiotherapy for pelvic lymphoceles following surgery for urological cancer: A case study.

Stefan Janssen1, Lukas Käsmann2, Robert Cegla3, Dirk Rades2.   

Abstract

The aim of the present study was to evaluate the outcome and toxicity of 3D conformal radiotherapy (RT) for persistent lymphoceles following surgery for urological cancer. A total of 6 patients with bladder (n=1) and prostate cancer (n=5), with persistent lymphoceles following surgery for a primary tumor were treated with total doses of 10-12 Gy (1 Gy single dose) after computed tomography (CT) based 3D planning in order to suspend secretion. No acute or chronic toxicities were observed. In 5 patients, secretion of lymph fluid resolved after RT and in 1 patient RT had no effect. After a mean follow-up of 21 months (range, 5-47 months), no patient suffered from any symptoms concerning his former lymphoceles. This is the first analysis, to the best of our knowledge, to evaluate a homogenous patient collective of urological cancer patients with persistent lymphoceles after surgery for the initial tumor. RT to lymphoceles in urological cancer patient is effective, very well-tolerated and should be offered to patients with persistent secretion following drainage.

Entities:  

Keywords:  postoperative lymphoceles; radiotherapy; urological cancer

Year:  2016        PMID: 27446576      PMCID: PMC4950563          DOI: 10.3892/mco.2016.933

Source DB:  PubMed          Journal:  Mol Clin Oncol        ISSN: 2049-9450


  7 in total

1.  [Radiotherapy of lymphatic fistula and lymphocele].

Authors:  B Neu; G Gauss; W Haase; J Dentz; K J Husfeldt
Journal:  Strahlenther Onkol       Date:  2000-01       Impact factor: 3.621

Review 2.  [Lymphoceles after radical retropubic prostatectomy. A treatment algorithm].

Authors:  P Anheuser; A Treiyer; E Stark; B Haben; J A Steffens
Journal:  Urologe A       Date:  2010-07       Impact factor: 0.639

3.  [Radiotherapy of inguinal lymphorrhea after vascular surgery. A retrospective analysis].

Authors:  Barbara Dietl; Karin Pfister; Carina Aufschläger; Piotr M Kasprzak
Journal:  Strahlenther Onkol       Date:  2005-06       Impact factor: 3.621

4.  Lymphatic fistulas: obliteration by low-dose radiotherapy.

Authors:  Ramona Mayer; Peter Sminia; William H McBride; Heidi Stranzl; Ulrike Prettenhofer; Johannes Fruhwirth; Johann Poschauko
Journal:  Strahlenther Onkol       Date:  2005-10       Impact factor: 3.621

5.  Radiotherapy in Prostate Cancer Patients With Pelvic Lymphocele After Surgery: Clinical and Dosimetric Data of 30 Patients.

Authors:  Barbara Alicja Jereczek-Fossa; Sarah Pia Colangione; Cristiana Fodor; Stefania Russo; Raffaella Cambria; Dario Zerini; Maria Bonora; Agnese Cecconi; Barbara Vischioni; Andrea Vavassori; Deliu Victor Matei; Danilo Bottero; Antonio Brescia; Gennaro Musi; Federica Mazzoleni; Franco Orsi; Guido Bonomo; Ottavio De Cobelli; Roberto Orecchia
Journal:  Clin Genitourin Cancer       Date:  2014-11-20       Impact factor: 2.872

6.  Complications of pelvic lymphadenectomy in 1,380 patients undergoing radical retropubic prostatectomy between 1993 and 2006.

Authors:  Michael Musch; Virgilijus Klevecka; Ulla Roggenbuck; Darko Kroepfl
Journal:  J Urol       Date:  2008-01-22       Impact factor: 7.450

7.  Management of pelvic lymphoceles following robot-assisted laparoscopic radical prostatectomy.

Authors:  Omer A Raheem; Wassim M Bazzi; J Kellogg Parsons; Christopher J Kane
Journal:  Urol Ann       Date:  2012-05
  7 in total
  1 in total

Review 1.  [Radiotherapeutic management of lymphatic fistulas : An effective but disregarded therapy option].

Authors:  D Habermehl; G Habl; H-H Eckstein; F Meisner; S E Combs
Journal:  Chirurg       Date:  2017-04       Impact factor: 0.955

  1 in total

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