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Literature DB >> 2744642

Rapid determination of the human complement factor B phenotypes.

Abstract

A rapid phenotyping method for human complement factor B (Bf) was worked out using high voltage acetate electrophoresis. The results were compared with those obtained by conventional agarose gel electrophoresis. Separation of the bands was performed in the same way, but only 2.5 hours were required for the evaluation of 24 samples. Furthermore, at least ten times less specific antibody was needed than for the conventional technique.

Entities: Chemical Gene Species

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Year: 1989 PMID： 2744642

Source DB: PubMed Journal: Haematologia (Budap) ISSN： 0017-6559

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Cited

1 in total

1. A marked drop in the incidence of the null allele of the B gene of the fourth component of complement (C4BQ0) in elderly subjects: C4BQ0 as a probable negative selection factor for survival.

Authors: J Kramer; T Fülöp; K Rajczy; A T Nguyen; G Füst
Journal: Hum Genet Date: 1991-04 Impact factor: 4.132

1 in total

Rapid determination of the human complement factor B phenotypes.

1. A marked drop in the incidence of the null allele of the B gene of the fourth component of complement (C4B*Q0) in elderly subjects: C4B*Q0 as a probable negative selection factor for survival.

1. A marked drop in the incidence of the null allele of the B gene of the fourth component of complement (C4BQ0) in elderly subjects: C4BQ0 as a probable negative selection factor for survival.