Literature DB >> 27444577

A tutorial introduction to Bayesian inference for stochastic epidemic models using Approximate Bayesian Computation.

Theodore Kypraios1, Peter Neal2, Dennis Prangle3.   

Abstract

Likelihood-based inference for disease outbreak data can be very challenging due to the inherent dependence of the data and the fact that they are usually incomplete. In this paper we review recent Approximate Bayesian Computation (ABC) methods for the analysis of such data by fitting to them stochastic epidemic models without having to calculate the likelihood of the observed data. We consider both non-temporal and temporal-data and illustrate the methods with a number of examples featuring different models and datasets. In addition, we present extensions to existing algorithms which are easy to implement and provide an improvement to the existing methodology. Finally, R code to implement the algorithms presented in the paper is available on https://github.com/kypraios/epiABC.
Copyright © 2016 Elsevier Inc. All rights reserved.

Keywords:  Approximate Bayesian Computation; Bayesian inference; Epidemics; Population Monte Carlo; Stochastic epidemic models

Mesh:

Year:  2016        PMID: 27444577     DOI: 10.1016/j.mbs.2016.07.001

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


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