Literature DB >> 27443940

A scientist's guide for submitting data to ZFIN.

D G Howe1, Y M Bradford1, A Eagle1, D Fashena1, K Frazer1, P Kalita1, P Mani1, R Martin1, S T Moxon1, H Paddock1, C Pich1, S Ramachandran1, L Ruzicka1, K Schaper1, X Shao1, A Singer1, S Toro1, C Van Slyke1, M Westerfield1.   

Abstract

The Zebrafish Model Organism Database (ZFIN; zfin.org) serves as the central repository for genetic and genomic data produced using zebrafish (Danio rerio). Data in ZFIN are either manually curated from peer-reviewed publications or submitted directly to ZFIN from various data repositories. Data types currently supported include mutants, transgenic lines, DNA constructs, gene expression, phenotypes, antibodies, morpholinos, TALENs, CRISPRs, disease models, movies, and images. The rapidly changing methods of genomic science have increased the production of data that cannot readily be represented in standard journal publications. These large data sets require web-based presentation. As the central repository for zebrafish research data, it has become increasingly important for ZFIN to provide the zebrafish research community with support for their data sets and guidance on what is required to submit these data to ZFIN. Regardless of their volume, all data that are submitted for inclusion in ZFIN must include a minimum set of information that describes the data. The aim of this chapter is to identify data types that fit into the current ZFIN database and explain how to provide those data in the optimal format for integration. We identify the required and optional data elements, define jargon, and present tools and templates that can help with the acquisition and organization of data as they are being prepared for submission to ZFIN. This information will also appear in the ZFIN wiki, where it will be updated as our services evolve over time.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Direct data submission; Gene expression; Model organism database; Mutant; Phenotype; Transgenic

Mesh:

Substances:

Year:  2016        PMID: 27443940      PMCID: PMC6319372          DOI: 10.1016/bs.mcb.2016.04.010

Source DB:  PubMed          Journal:  Methods Cell Biol        ISSN: 0091-679X            Impact factor:   1.441


  14 in total

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Authors:  Ceri E Van Slyke; Yvonne M Bradford; Monte Westerfield; Melissa A Haendel
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8.  ZFIN, the Zebrafish Model Organism Database: increased support for mutants and transgenics.

Authors:  Douglas G Howe; Yvonne M Bradford; Tom Conlin; Anne E Eagle; David Fashena; Ken Frazer; Jonathan Knight; Prita Mani; Ryan Martin; Sierra A Taylor Moxon; Holly Paddock; Christian Pich; Sridhar Ramachandran; Barbara J Ruef; Leyla Ruzicka; Kevin Schaper; Xiang Shao; Amy Singer; Brock Sprunger; Ceri E Van Slyke; Monte Westerfield
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  5 in total

1.  The Zebrafish Model Organism Database: new support for human disease models, mutation details, gene expression phenotypes and searching.

Authors:  Douglas G Howe; Yvonne M Bradford; Anne Eagle; David Fashena; Ken Frazer; Patrick Kalita; Prita Mani; Ryan Martin; Sierra Taylor Moxon; Holly Paddock; Christian Pich; Sridhar Ramachandran; Leyla Ruzicka; Kevin Schaper; Xiang Shao; Amy Singer; Sabrina Toro; Ceri Van Slyke; Monte Westerfield
Journal:  Nucleic Acids Res       Date:  2016-11-28       Impact factor: 16.971

2.  Micropublication: incentivizing community curation and placing unpublished data into the public domain.

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3.  Endoglin is a conserved regulator of vasculogenesis in zebrafish - implications for hereditary haemorrhagic telangiectasia.

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4.  ZebraShare: a new venue for rapid dissemination of zebrafish mutant data.

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  5 in total

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