Literature DB >> 27443855

Assessing the inhalation cancer risk of particulate matter bound polycyclic aromatic hydrocarbons (PAHs) for the elderly in a retirement community of a mega city in North China.

Bin Han1, Yating Liu2, Yan You3, Jia Xu1, Jian Zhou4, Jiefeng Zhang5, Can Niu3, Nan Zhang1, Fei He6, Xiao Ding7, Zhipeng Bai8.   

Abstract

Assessment of the health risks resulting from exposure to ambient polycyclic aromatic hydrocarbons (PAHs) is limited by the lack of environmental exposure data among different subpopulations. To assess the exposure cancer risk of particulate carcinogenic polycyclic aromatic hydrocarbon pollution for the elderly, this study conducted a personal exposure measurement campaign for particulate PAHs in a community of Tianjin, a city in northern China. Personal exposure samples were collected from the elderly in non-heating (August-September, 2009) and heating periods (November-December, 2009), and 12 PAHs individuals were analyzed for risk estimation. Questionnaire and time-activity log were also recorded for each person. The probabilistic risk assessment model was integrated with Toxic Equivalent Factors (TEFs). Considering that the estimation of the applied dose for a given air pollutant is dependent on the inhalation rate, the inhalation rate from both EPA exposure factor book was applied to calculate the carcinogenic risk in this study. Monte Carlo simulation was used as a probabilistic risk assessment model, and risk simulation results indicated that the inhalation-ILCR values for both male and female subjects followed a lognormal distribution with a mean of 4.81 × 10-6 and 4.57 × 10-6, respectively. Furthermore, the 95 % probability lung cancer risks were greater than the USEPA acceptable level of 10-6 for both men and women through the inhalation route, revealing that exposure to PAHs posed an unacceptable potential cancer risk for the elderly in this study. As a result, some measures should be taken to reduce PAHs pollution and the exposure level to decrease the cancer risk for the general population, especially for the elderly.

Entities:  

Keywords:  Elderly; Inhalation rate; Monte Carlo simulation; PAHs; Personal exposure; Risk assessment; Tianjin

Mesh:

Substances:

Year:  2016        PMID: 27443855     DOI: 10.1007/s11356-016-7209-9

Source DB:  PubMed          Journal:  Environ Sci Pollut Res Int        ISSN: 0944-1344            Impact factor:   4.223


  28 in total

1.  Mutagenic activity of airborne particulates at non-industrial locations.

Authors:  G M Alink; H A Smit; J J van Houdt; J R Kolkman; J S Boleij
Journal:  Mutat Res       Date:  1983-01       Impact factor: 2.433

2.  Exposure of traffic police to Polycyclic aromatic hydrocarbons in Beijing, China.

Authors:  Y N Liu; S Tao; H Dou; T W Zhang; X L Zhang; R Dawson
Journal:  Chemosphere       Date:  2006-09-25       Impact factor: 7.086

3.  Genotoxic damage in female residents exposed to environmental air pollution in Shenyang city, China.

Authors:  Hitoshi Ishikawa; Ying Tian; Fengyuan Piao; Zhiwen Duan; Yumin Zhang; Mingyue Ma; Haishan Li; Hidetaka Yamamoto; Yutaka Matsumoto; Shigekatsu Sakai; Jinshan Cui; Toru Yamauchi; Kazuhito Yokoyama
Journal:  Cancer Lett       Date:  2005-10-21       Impact factor: 8.679

4.  Formation of polycyclic aromatic hydrocarbons from tobacco: the link between low temperature residual solid (char) and PAH formation.

Authors:  Thomas E McGrath; Jan B Wooten; W Geoffrey Chan; Mohammad R Hajaligol
Journal:  Food Chem Toxicol       Date:  2006-12-24       Impact factor: 6.023

5.  Personal inhalation exposure to polycyclic aromatic hydrocarbons in urban and rural residents in a typical northern city in China.

Authors:  X Duan; B Wang; X Zhao; G Shen; Z Xia; N Huang; Q Jiang; B Lu; D Xu; J Fang; S Tao
Journal:  Indoor Air       Date:  2014-03-12       Impact factor: 5.770

Review 6.  Risk assessment for benzo[a]pyrene.

Authors:  J F Collins; J P Brown; S V Dawson; M A Marty
Journal:  Regul Toxicol Pharmacol       Date:  1991-04       Impact factor: 3.271

7.  Assessing hazardous risks of human exposure to temple airborne polycyclic aromatic hydrocarbons.

Authors:  Kuo-Chih Chiang; Chia-Pin Chio; Yu-Hui Chiang; Chung-Min Liao
Journal:  J Hazard Mater       Date:  2008-12-03       Impact factor: 10.588

8.  Health risk assessment for vehicle inspection workers exposed to airborne polycyclic aromatic hydrocarbons (PAHs) in their work place.

Authors:  Peng-hui Li; Shao-fei Kong; Chun-mei Geng; Bin Han; Bing Lu; Ru-feng Sun; Ruo-jie Zhao; Zhi-peng Bai
Journal:  Environ Sci Process Impacts       Date:  2013-03       Impact factor: 4.238

Review 9.  Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.

Authors:  Carl-Elis Boström; Per Gerde; Annika Hanberg; Bengt Jernström; Christer Johansson; Titus Kyrklund; Agneta Rannug; Margareta Törnqvist; Katarina Victorin; Roger Westerholm
Journal:  Environ Health Perspect       Date:  2002-06       Impact factor: 9.031

10.  Estimating individual-level exposure to airborne polycyclic aromatic hydrocarbons throughout the gestational period based on personal, indoor, and outdoor monitoring.

Authors:  Hyunok Choi; Frederica Perera; Agnieszka Pac; Lu Wang; Elzbieta Flak; Elzbieta Mroz; Ryszard Jacek; Tricia Chai-Onn; Wieslaw Jedrychowski; Elizabeth Masters; David Camann; John Spengler
Journal:  Environ Health Perspect       Date:  2008-07-16       Impact factor: 9.031

View more
  4 in total

Review 1.  Relationships between chronic obstructive pulmonary disease and lung cancer: biological insights.

Authors:  Esther Barreiro; Víctor Bustamante; Víctor Curull; Joaquim Gea; José Luis López-Campos; Xavier Muñoz
Journal:  J Thorac Dis       Date:  2016-10       Impact factor: 2.895

2.  PM Origin or Exposure Duration? Health Hazards from PM-Bound Mercury and PM-Bound PAHs among Students and Lecturers.

Authors:  Grzegorz Majewski; Kamila Widziewicz; Wioletta Rogula-Kozłowska; Patrycja Rogula-Kopiec; Karolina Kociszewska; Tomasz Rozbicki; Małgorzata Majder-Łopatka; Mariusz Niemczyk
Journal:  Int J Environ Res Public Health       Date:  2018-02-12       Impact factor: 3.390

3.  Source Apportionment of Coarse Particulate Matter (PM10) in Yangon, Myanmar.

Authors:  Piyaporn Sricharoenvech; Alexandra Lai; Tin Nwe Oo; Min M Oo; James J Schauer; Kyi Lwin Oo; Kay Khine Aye
Journal:  Int J Environ Res Public Health       Date:  2020-06-10       Impact factor: 3.390

4.  Relationship Between Polycyclic Aromatic Hydrocarbons and Cardiovascular Diseases: A Systematic Review.

Authors:  Manthar Ali Mallah; Mukhtiar Ali Mallah; Yang Liu; He Xi; Wei Wang; Feifei Feng; Qiao Zhang
Journal:  Front Public Health       Date:  2021-12-07
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.