| Literature DB >> 27443134 |
Kurt W Prins1, Thenappan Thenappan2.
Abstract
Pulmonary arterial hypertension (PAH) is a debilitating disease characterized by pathologic remodeling of the resistance pulmonary arteries, ultimately leading to right ventricular (RV) failure and death. In this article we discuss the definition of PAH, the initial epidemiology based on the National Institutes of Health Registry, and the updated epidemiology gleaned from contemporary registries, pathogenesis of pulmonary vascular dysfunction and proliferation, and RV failure in PAH.Entities:
Keywords: Epidemiology; Pathophysiology; Pulmonary arterial hypertension; Pulmonary vasculature; Right ventricle
Mesh:
Year: 2016 PMID: 27443134 PMCID: PMC4959804 DOI: 10.1016/j.ccl.2016.04.001
Source DB: PubMed Journal: Cardiol Clin ISSN: 0733-8651 Impact factor: 2.213