Literature DB >> 27442394

Effect of Adding Dexamethasone as a Ropivacaine Adjuvant in Ultrasound-Guided Transversus Abdominis Plane Block for Inguinal Hernia Repair.

Andrijan Kartalov, Nikola Jankulovski, Biljana Kuzmanovska, Milka Zdravkovska, Mirjana Shosholcheva, Tatjana Spirovska, Aleksandra Panovska Petrusheva, Marija Tolevska, Marija Srceva, Vesna Durnev, Gjorgji Jota, Redzep Selmani, Atanas Sivevski.   

Abstract

BACKGROUND: The transverses abdominals plane block (TAP) is a regional anesthesia technique that provided analgesia to the parietal peritoneum, skin and muscles of the anterior abdominal wall. The aim of this randomized double-blind study was to evaluate postoperative analgesia on patients undergoing open inguinal hernia repair under general anesthesia (GA), (GA + TAP) block preformed with ropivacaine and (GA + TAP-D) block preformed with ropivacaine and 4 mg dexamethasone.
METHODS: 90 (ASA I-II) adult patients for unilateral open inguinal hernia repair were included in this study. In group I (n = 30) patents received only general anesthesia (GA). Patients in group II (n = 30) received GA and unilateral TAP block with 25 ml of 0.5% ropivacaine and the patients in group III (n = 30) received GA and unilateral TAP-D block with 25 ml of 0.5% ropivacaine + 4 mg Dexamethadsone. In this study we assessed the pain score - VAS at rest at 2, 4, 6, 12 and 24 hours after the operation and the total analgesic consumption of morphine over 24 hours.
RESULTS: There were statistically significant differences in the VAS scores between group I, group II and group III at all postoperative time points - 2(hr), 4(hr), 6(hr), 12(hr) and 24(hr). (p < 0.00001). The cumulative 24 hours morphine consumption after the operation was significantly lower in group III (5.53 1.21 mg) than in group II (6.16 2.41 mg) and group I (9.26 2.41 mg). This difference is statistically significant (p < 0.00001).
CONCLUSION: Concerning the inguinal hernia repair we found better postoperative pain scores and 24 hours reduction of the morphine consumption in group III (GA and TAP-D block) compared with group I (GA) and group II (GA + TAP block).

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Year:  2015        PMID: 27442394     DOI: 10.1515/prilozi-2015-0076

Source DB:  PubMed          Journal:  Pril (Makedon Akad Nauk Umet Odd Med Nauki)        ISSN: 1857-9345


  9 in total

Review 1.  Adjuvant Agents in Regional Anesthesia in the Ambulatory Setting.

Authors:  Veerandra Koyyalamudi; Sudipta Sen; Shilpadevi Patil; Justin B Creel; Elyse M Cornett; Charles J Fox; Alan D Kaye
Journal:  Curr Pain Headache Rep       Date:  2017-01

2.  Efficacy of Nalbuphine with Flurbiprofen on Multimodal Analgesia with Transverse Abdominis Plane Block in Elderly Patients Undergoing Open Gastrointestinal Surgery: A Randomized, Controlled, Double-Blinded Trial.

Authors:  Yu Mao; Yuanyuan Cao; Bin Mei; Lijian Chen; Xuesheng Liu; Zhi Zhang; Erwei Gu
Journal:  Pain Res Manag       Date:  2018-01-28       Impact factor: 3.037

3.  Effect of addition of dexamethasone to ropivacaine on post-operative analgesia in ultrasonography-guided transversus abdominis plane block for inguinal hernia repair: A prospective, double-blind, randomised controlled trial.

Authors:  Uma Datt Sharma; Himani Tak
Journal:  Indian J Anaesth       Date:  2018-05

4.  Dexamethasone added to local anesthetics in ultrasound-guided transversus abdominis plain (TAP) block for analgesia after abdominal surgery: A systematic review and meta-analysis of randomized controlled trials.

Authors:  Donghang Zhang; Cheng Zhou; Dang Wei; Long Ge; Qian Li
Journal:  PLoS One       Date:  2019-01-08       Impact factor: 3.240

5.  Analgesic efficacy of dexamethasone versus dexmedetomidine as an adjuvant to ropivacaine in ultrasound-guided transversus abdominis plane block for post-operative pain relief in caesarean section: A prospective randomised controlled study.

Authors:  Nitika Singla; Kamakshi Garg; Richa Jain; Aaina Malhotra; Mirley Rupinder Singh; Anju Grewal
Journal:  Indian J Anaesth       Date:  2021-09-15

6.  Regional block anesthesia for adult patients with inguinal hernia repair: A systematic review.

Authors:  Jie Lv; Qi Zhang; Ting Zeng; Xue-Feng Li; Yang Cui
Journal:  Medicine (Baltimore)       Date:  2022-09-23       Impact factor: 1.817

7.  An Evaluation of the Adding Magnesium Sulfate to Ropivacaine on Ultrasound-Guided Transverse Abdominis Plane Block After Abdominal Hysterectomy.

Authors:  Farnad Imani; Poupak Rahimzadeh; Hamid-Reza Faiz; Alireza Abdullahzadeh-Baghaei
Journal:  Anesth Pain Med       Date:  2018-07-29

8.  Clinical analgesic efficacy of dexamethasone as a local anesthetic adjuvant for transversus abdominis plane (TAP) block: A meta-analysis.

Authors:  Qi Chen; Ran An; Ju Zhou; Bin Yang
Journal:  PLoS One       Date:  2018-06-14       Impact factor: 3.240

9.  Comparative Evaluation of Ropivacaine and Ropivacaine with Dexamethasone in Transverse Abdominis Plane Block for Lower Abdominal Surgeries: A Prospective, Randomized, Double-Blinded Study.

Authors:  N Gnanasekar; G Dilip Kumar; Pranjali Kurhekar; M S Raghuraman; T Krishna Prasad
Journal:  Anesth Essays Res       Date:  2018 Oct-Dec
  9 in total

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