Literature DB >> 27440873

Lost opportunity to save newborn lives: variable national antenatal screening policies for Neisseria gonorrhoeae and Chlamydia trachomatis.

Alexandra Medline1, Dvora Joseph Davey2,3, Jeffrey D Klausner2.   

Abstract

Unfavorable pregnancy outcomes caused by Chlamydia trachomatis or Neisseria gonorrhoeae infection are well known. The first step in addressing antenatal C. trachomatis and N. gonorrhoeae infection is a national policy to screen all pregnant women for C. trachomatis and N. gonorrhoeae, regardless of symptoms. The aim of this study was to inform policy makers on the presence of antenatal screening recommendations for C. trachomatis and N. gonorrhoeae infection. We conducted a three-part study from June 2015 to February 2016. We analyzed English and French language information online on Ministry of Health websites regarding C. trachomatis and N. gonorrhoeae antenatal screening. We referenced both primary official country and regional policy documents. We contacted the Ministry of Health directly if the information on the national antenatal screening was outdated or unavailable. In parallel, we sent a survey to the regional representative from the World Health Organization to help collect country-level data. Fourteen countries have current policies for antenatal screening of C. trachomatis and/or N. gonorrhoeae infection: Australia, the Bahamas, Bulgaria, Canada, Estonia, Japan, Germany, Latvia, New Zealand, Democratic People's Republic of Korea, Romania, Sweden, the United Kingdom, and the United States. Australia, New Zealand, and Latvia and the United States restricted antenatal screening to women ≤25 years old and those of higher risk. Several countries responded that they had policies to treat pregnant women with symptoms. This is the currently recommended WHO guideline but is not the same as universal screening. North Korea had policies in place which were not implemented due to lack of personnel and/or supplies. National level policies to support routine screening for C. trachomatis and N. gonorrhoeae infection to prevent adverse pregnancy and newborn outcomes are uncommon.

Entities:  

Keywords:  Chlamydia (Chlamydia trachomatis); gonorrhea (Neisseria gonorrhoeae); prevention; screening; women

Mesh:

Year:  2016        PMID: 27440873      PMCID: PMC6879101          DOI: 10.1177/0956462416660483

Source DB:  PubMed          Journal:  Int J STD AIDS        ISSN: 0956-4624            Impact factor:   1.359


  35 in total

1.  Chlamydial and gonococcal testing during pregnancy in the United States.

Authors:  Amy J Blatt; Jay M Lieberman; Donald R Hoover; Harvey W Kaufman
Journal:  Am J Obstet Gynecol       Date:  2012-04-30       Impact factor: 8.661

2.  Chlamydia screening for pregnant women aged 16-25 years attending an antenatal service: a cost-effectiveness study.

Authors:  J J Ong; M Chen; J Hocking; C K Fairley; R Carter; L Bulfone; A Hsueh
Journal:  BJOG       Date:  2015-08-26       Impact factor: 6.531

3.  High prevalence of sexually transmitted infections in pregnant adolescent girls in Tanzania: a multi-community cross-sectional study.

Authors:  Adolfine Hokororo; Albert Kihunrwa; Pytsje Hoekstra; Samuel E Kalluvya; John M Changalucha; Daniel W Fitzgerald; Jennifer A Downs
Journal:  Sex Transm Infect       Date:  2015-04-01       Impact factor: 3.519

4.  Prevalence and risk factors for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis infection in pregnant women in Papua New Guinea.

Authors:  R A Wangnapi; S Soso; H W Unger; C Sawera; M Ome; A J Umbers; N Ndrewei; P Siba; C S N Li Wai Suen; A Vallely; J Wapling; C Ryan; I Mueller; S J Rogerson
Journal:  Sex Transm Infect       Date:  2014-10-13       Impact factor: 3.519

Review 5.  Prevalence of Curable Sexually Transmitted Infections in Pregnant Women in Low- and Middle-Income Countries From 2010 to 2015: A Systematic Review.

Authors:  D L Joseph Davey; H I Shull; J D Billings; D Wang; K Adachi; J D Klausner
Journal:  Sex Transm Dis       Date:  2016-07       Impact factor: 2.830

6.  Maternal Chlamydia trachomatis infections and preterm birth:the impact of early detection and eradication during pregnancy.

Authors:  Alonzo T Folger
Journal:  Matern Child Health J       Date:  2014-10

7.  [Screening for asymptomatic Chlamydia trachomatis infection in pregnancy; cost-effectiveness favorable at a minimum prevalence rate of 3% or more].

Authors:  M J Postma; A Bakker; R Welte; J E van Bergen; J A van den Hoek; L T de Jong-van den Berg; J C Jager
Journal:  Ned Tijdschr Geneeskd       Date:  2000-12-02

Review 8.  Genital Chlamydia trachomatis infections.

Authors:  C Bébéar; B de Barbeyrac
Journal:  Clin Microbiol Infect       Date:  2009-01       Impact factor: 8.067

9.  Preventing ophthalmia neonatorum.

Authors:  Dorothy L Moore; Noni E MacDonald
Journal:  Can J Infect Dis Med Microbiol       Date:  2015 May-Jun       Impact factor: 2.471

10.  Gynaecological morbidity among HIV positive pregnant women in Cameroon.

Authors:  Enow R Mbu; Eugene J Kongnyuy; F X Mbopi-Keou; Rebecca N Tonye; Philip N Nana; Robert J I Leke
Journal:  Reprod Health       Date:  2008-07-03       Impact factor: 3.223

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  14 in total

1.  Keep Screening! Maternal Gonococcal Infection and Adverse Birth Outcomes.

Authors:  Chelsea Lee Shannon; Jeffrey D Klausner
Journal:  Sex Transm Dis       Date:  2017-05       Impact factor: 2.830

2.  Acceptability and Feasibility of Rapid Chlamydial, Gonococcal, and Trichomonal Screening and Treatment in Pregnant Women in 6 Low- to Middle-Income Countries.

Authors:  Chelsea Lee Shannon; Claire Bristow; Nicole Hoff; Adriane Wynn; Minh Nguyen; Andrew Medina-Marino; Jeanne Cabeza; Anne Rimoin; Jeffrey D Klausner
Journal:  Sex Transm Dis       Date:  2018-10       Impact factor: 2.830

3.  Prevalence and treatment outcomes of routine Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana.

Authors:  Adriane Wynn; Doreen Ramogola-Masire; Ponatshego Gaolebale; Neo Moshashane; Ontiretse Sickboy; Sofia Duque; Elizabeth Williams; Klara Doherty; Jeffrey D Klausner; Chelsea Morroni
Journal:  Sex Transm Infect       Date:  2017-11-02       Impact factor: 3.519

4.  High prevalence of asymptomatic sexually transmitted infections among human immunodeficiency virus-infected pregnant women in a low-income South African community.

Authors:  Maanda Mudau; Remco P Peters; Lindsey De Vos; Dawie H Olivier; Dvora J Davey; Edwin S Mkwanazi; James A McIntyre; Jeffrey D Klausner; Andrew Medina-Marino
Journal:  Int J STD AIDS       Date:  2017-08-11       Impact factor: 1.359

Review 5.  A review on Trichomonas vaginalis infections in women from Africa.

Authors:  Nonkululeko Mabaso; Nathlee S Abbai
Journal:  S Afr J Infect Dis       Date:  2021-06-10

6.  Cost-effectiveness analysis of Chlamydia trachomatis screening in Dutch pregnant women.

Authors:  G I J G Rours; Tamar Anne Smith-Norowitz; Jared Ditkowsky; Margaret R Hammerschlag; R P Verkooyen; R de Groot; H A Verbrugh; M J Postma
Journal:  Pathog Glob Health       Date:  2016 Oct - Dec       Impact factor: 2.894

Review 7.  Sexually transmitted infections in pregnant women from sub-Saharan Africa.

Authors:  Bongekile Ngobese; Nathlee S Abbai
Journal:  S Afr J Infect Dis       Date:  2021-12-09

8.  Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women.

Authors:  E Morikawa; M Mudau; D Olivier; L de Vos; D Joseph Davey; C Price; J A McIntyre; R P Peters; J D Klausner; A Medina-Marino
Journal:  Infect Dis Obstet Gynecol       Date:  2018-05-09

Review 9.  Sexually Transmitted Infections in Pregnancy: A Narrative Review of the Global Research Gaps, Challenges, and Opportunities.

Authors:  Juliana S Grant; R Matthew Chico; Anne Cc Lee; Nicola Low; Andrew Medina-Marino; Rose L Molina; Chelsea Morroni; Doreen Ramogola-Masire; Chrysovalantis Stafylis; Weiming Tang; Andrew J Vallely; Adriane Wynn; Nava Yeganeh; Jeffrey D Klausner
Journal:  Sex Transm Dis       Date:  2020-12       Impact factor: 3.868

Review 10.  Chlamydia trachomatis Screening and Treatment in Pregnancy to Reduce Adverse Pregnancy and Neonatal Outcomes: A Review.

Authors:  Kristina N Adachi; Karin Nielsen-Saines; Jeffrey D Klausner
Journal:  Front Public Health       Date:  2021-06-10
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