Literature DB >> 27440849

A case of isolated renal involvement of polyarteritis nodosa successfully treated with steroid monotherapy.

Negiin Pourafshar1, Eric Sobel2, Mark Segal1.   

Abstract

Polyarteritis nodosa (PAN) is a systemic necrotising vasculitis that affects medium-sized and small-sized arteries. The spectrum of disease ranges from involving a single organ to polyvisceral failure. We report a case of a 75-year-old male presented with solely hypertension and mild renal function impairment as a consequence of diffuse renal necrotising vasculitis with occlusive but non-stenotic lesions associated with PAN. The overall prognosis of PAN has been improved in recent decades, primarily reflecting early diagnosis and more effective treatments. Therefore, early diagnosis is critical and it warrants full investigations even in those patients without obvious multiorgan manifestations. In those instances, with mild disease, steroid monotherapy has been shown to be effective with excellent response. Our patient responded well to steroid monotherapy and we were able to gauge his response by improvement in his blood pressure. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27440849      PMCID: PMC4964193          DOI: 10.1136/bcr-2016-215702

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  18 in total

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5.  Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies.

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6.  Treatment of polyarteritis nodosa and microscopic polyangiitis with poor prognosis factors: a prospective trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in sixty-five patients.

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Review 7.  Vasculitis mimics.

Authors:  Eamonn S Molloy; Carol A Langford
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9.  The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa.

Authors:  R W Lightfoot; B A Michel; D A Bloch; G G Hunder; N J Zvaifler; D J McShane; W P Arend; L H Calabrese; R Y Leavitt; J T Lie
Journal:  Arthritis Rheum       Date:  1990-08

10.  Hypertension, hyperreninemia, and secondary hyperaldosteronism in systemic necrotizing vasculitis.

Authors:  R H White; M Schambelan
Journal:  Ann Intern Med       Date:  1980-02       Impact factor: 25.391

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Review 1.  Localized Forms of Vasculitis.

Authors:  Joana Martins-Martinho; Eduardo Dourado; Nikita Khmelinskii; Pablo Espinosa; Cristina Ponte
Journal:  Curr Rheumatol Rep       Date:  2021-07-01       Impact factor: 4.592

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