Neha A Kajale1, Vaman V Khadilkar1, Zulf Mughal2, Shashi A Chiplonkar1, Anuradha V Khadilkar3. 1. Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India. 2. Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK. 3. Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India. Email: anuradhavkhadilkar@gmail.com.
Abstract
BACKGROUND AND OBJECTIVES: Lactation places enormous demands on maternal bone mineral homeostasis. Indian middle class women (MSC) consume energy dense food supplements to meet these demands post-partum (PP) along with restricted physical activity (PA). Effects of these changes on body composition (BC) of PP women have not been studied. To examine longitudinal changes in: a) bone mineral density (BMD) at total body (TB), AP-spine (APS) and dual femur neck regions (DF) b) BC by body weight, lean mass, fat mass using dual energy X-ray absorptiometry (DXA) at baseline, 6-months and 1-year in urban MSC women. METHODS AND STUDY DESIGN: 76-primi-parous (28±3.2 yrs) randomly selected PP women (<7-days) were studied; 70 reassessed at 6- months and 42 1-yr PP. Data on anthropometry, BC, BMD at TB, APS and DF by DXA collected (baseline, 6- months, 1-yr PP). RESULTS: Weight, waist and body mass index (BMI) decreased both at 6-month and 1-yr PP with respect to baseline (p<0.05). BC changes showed increase in android fat % at 1-yr by 10% over baseline (p<0.05). BMD with initial decline at 6-months (-2.8%, -2.3% and -2.3% respectively) recovered partially by 1-yr (+2.5% +1.2% and +4.8% respectively) at DF and TB with complete recovery at APS (p<0.05). CONCLUSION: These urban relatively sedentary MSC women consumed fat rich food PP with higher android fat retention and partial recovery of BMD at DF and TB at 1-year. Modifications in activity and dietary nutrient intakes may be necessary to prevent cardiovascular and bone health related risks.
BACKGROUND AND OBJECTIVES: Lactation places enormous demands on maternal bone mineral homeostasis. Indian middle class women (MSC) consume energy dense food supplements to meet these demands post-partum (PP) along with restricted physical activity (PA). Effects of these changes on body composition (BC) of PP women have not been studied. To examine longitudinal changes in: a) bone mineral density (BMD) at total body (TB), AP-spine (APS) and dual femur neck regions (DF) b) BC by body weight, lean mass, fat mass using dual energy X-ray absorptiometry (DXA) at baseline, 6-months and 1-year in urban MSC women. METHODS AND STUDY DESIGN: 76-primi-parous (28±3.2 yrs) randomly selected PP women (<7-days) were studied; 70 reassessed at 6- months and 42 1-yr PP. Data on anthropometry, BC, BMD at TB, APS and DF by DXA collected (baseline, 6- months, 1-yr PP). RESULTS: Weight, waist and body mass index (BMI) decreased both at 6-month and 1-yr PP with respect to baseline (p<0.05). BC changes showed increase in android fat % at 1-yr by 10% over baseline (p<0.05). BMD with initial decline at 6-months (-2.8%, -2.3% and -2.3% respectively) recovered partially by 1-yr (+2.5% +1.2% and +4.8% respectively) at DF and TB with complete recovery at APS (p<0.05). CONCLUSION: These urban relatively sedentary MSC women consumed fat rich food PP with higher android fat retention and partial recovery of BMD at DF and TB at 1-year. Modifications in activity and dietary nutrient intakes may be necessary to prevent cardiovascular and bone health related risks.
Authors: F M F Grizzo; M de Andrade Pereira; L B M Marchiotti; F Guilhem; T da Silva Santos; C M Dell' Agnolo; W A de Melo; M de Medeiros Pinheiro; M D de Barros Carvalho; S M Pelloso Journal: Osteoporos Int Date: 2021-01-21 Impact factor: 4.507
Authors: Sarah L McLennan; Amanda Henry; Lynne M Roberts; Sai S Siritharan; Melissa Ojurovic; Amanda Yao; Gregory K Davis; George Mangos; Franziska Pettit; Mark A Brown; Anthony J O'Sullivan Journal: J Clin Endocrinol Metab Date: 2021-07-13 Impact factor: 5.958
Authors: Neha A Kajale; Vaman Khadilkar; Shashi A Chiplonkar; Raja Padidela; Anuradha V Khadilkar Journal: Indian J Endocrinol Metab Date: 2017 Sep-Oct