Literature DB >> 27440665

What about microsaccades in the electroencephalogram of infants?

Moritz Köster1.   

Abstract

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Year:  2016        PMID: 27440665      PMCID: PMC4971203          DOI: 10.1098/rspb.2016.0739

Source DB:  PubMed          Journal:  Proc Biol Sci        ISSN: 0962-8452            Impact factor:   5.349


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Kampis et al. [1] use gamma oscillations (here 25–35 Hz) in the scalp-recorded electroencephalogram (EEG) of infants to investigate the neuronal signatures of objects representations. Oscillations in the gamma range have been used in several infant studies in the recent years [2-4] and are viewed as an important tool to investigate preverbal object representation processes [5,6]. However, Kampis et al. [1] (and the authors of the other studies mentioned above [2-4]) do not mention that they tested for microsaccadic eye movements in their subjects, which is critical when analysing gamma-band oscillations in the EEG. In the EEG of adults, Yuval-Greenberg et al. [7] have demonstrated beyond doubt that microsaccadic eye movements contaminate the gamma-band activity measured by the EEG and are, like neuronal gamma-band responses, sensitive to different cognitive processes, including object representation processes. This and further studies also revealed that the approximately 20–90 Hz activity elicited by microsaccades has a much higher amplitude than gamma-band activity elicited by neural object representation processes [7-9]. Since then, in the adult literature, gamma-band activity in the EEG has been commonly reported after the removal of microsaccadic artefacts, for example with independent component procedures [8,9] (for a summary, see [10]). Importantly, these studies demonstrate that gamma-band activity can still be observed after the removal of microsaccadic artefacts. Thus, gamma-band analyses in the EEG remain a useful tool to investigate neural object representation processes in adults, when microsaccadic artefacts are removed [11,12], and may also serve to understand these processes in infants. To conclude, in the study by Kampis et al. [1] and other recent EEG studies with infants [2-4] it is unclear whether microsaccadic eye movements are present and may contaminate the EEG signal, as in adults. The measured activity in the 25–35 Hz range may thus result from neuronal processes, eye movements or a mixture of both sources. I encourage the authors of this study and future studies investigating gamma-band oscillations in the infant EEG to clarify whether or not the EEG of infants is contaminated by similar microsaccadic eye movements as found in adults. Notably, if present, the characteristics of microsaccades of infants may differ from those in adults, and the development of age appropriate algorithms to remove microsaccadic artefacts in the EEG of infants is methodologically challenging. This would probably require the simultaneous application of EEG and eye-tracking methods, as well as relatively long periods of noise-free EEG recordings to run independent component analyses [7-9]. However, if microsaccadic artefacts should be present in the EEG of infants, only this would allow researchers to tear apart cognitive processes reflected in neural gamma-band oscillations and miniature eye movements, which possibly also reflect cognitive processes.
  10 in total

1.  Transient induced gamma-band response in EEG as a manifestation of miniature saccades.

Authors:  Shlomit Yuval-Greenberg; Orr Tomer; Alon S Keren; Israel Nelken; Leon Y Deouell
Journal:  Neuron       Date:  2008-05-08       Impact factor: 17.173

2.  Saccadic spike potentials in gamma-band EEG: characterization, detection and suppression.

Authors:  Alon S Keren; Shlomit Yuval-Greenberg; Leon Y Deouell
Journal:  Neuroimage       Date:  2009-10-27       Impact factor: 6.556

3.  Induced gamma band responses in human EEG after the control of miniature saccadic artifacts.

Authors:  Uwe Hassler; Nelson Trujillo Barreto; Thomas Gruber
Journal:  Neuroimage       Date:  2011-05-30       Impact factor: 6.556

4.  Theta-gamma coupling during episodic retrieval in the human EEG.

Authors:  Moritz Köster; Uwe Friese; Benjamin Schöne; Nelson Trujillo-Barreto; Thomas Gruber
Journal:  Brain Res       Date:  2014-06-27       Impact factor: 3.252

5.  Successful memory encoding is associated with increased cross-frequency coupling between frontal theta and posterior gamma oscillations in human scalp-recorded EEG.

Authors:  Uwe Friese; Moritz Köster; Uwe Hassler; Ulla Martens; Nelson Trujillo-Barreto; Thomas Gruber
Journal:  Neuroimage       Date:  2012-11-08       Impact factor: 6.556

Review 6.  The utility of EEG band power analysis in the study of infancy and early childhood.

Authors:  Joni N Saby; Peter J Marshall
Journal:  Dev Neuropsychol       Date:  2012       Impact factor: 2.253

7.  Enhancement of gamma oscillations indicates preferential processing of native over foreign phonemic contrasts in infants.

Authors:  Silvia Ortiz-Mantilla; Jarmo A Hämäläinen; Gabriella Musacchia; April A Benasich
Journal:  J Neurosci       Date:  2013-11-27       Impact factor: 6.167

8.  Verbal labels modulate perceptual object processing in 1-year-old children.

Authors:  Teodora Gliga; Agnes Volein; Gergely Csibra
Journal:  J Cogn Neurosci       Date:  2010-12       Impact factor: 3.225

9.  Oscillatory Activity in the Infant Brain and the Representation of Small Numbers.

Authors:  Sumie Leung; Denis Mareschal; Renee Rowsell; David Simpson; Leon Iaria; Amanda Grbic; Jordy Kaufman
Journal:  Front Syst Neurosci       Date:  2016-02-08

10.  Neural signatures for sustaining object representations attributed to others in preverbal human infants.

Authors:  Dora Kampis; Eugenio Parise; Gergely Csibra; Ágnes Melinda Kovács
Journal:  Proc Biol Sci       Date:  2015-11-22       Impact factor: 5.349

  10 in total
  3 in total

1.  On potential ocular artefacts in infant electroencephalogram: a reply to comments by Köster.

Authors:  Dora Kampis; Eugenio Parise; Gergely Csibra; Ágnes Melinda Kovács
Journal:  Proc Biol Sci       Date:  2016-07-27       Impact factor: 5.349

2.  Neuronal oscillations reveal the processes underlying intentional compared to incidental learning in children and young adults.

Authors:  Moritz Köster; André Haese; Daniela Czernochowski
Journal:  PLoS One       Date:  2017-08-02       Impact factor: 3.240

3.  Toward the Understanding of Topographical and Spectral Signatures of Infant Movement Artifacts in Naturalistic EEG.

Authors:  Stanimira Georgieva; Suzannah Lester; Valdas Noreika; Meryem Nazli Yilmaz; Sam Wass; Victoria Leong
Journal:  Front Neurosci       Date:  2020-04-28       Impact factor: 4.677

  3 in total

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