Chia-Fan Chang1,2,3, Yen-Ling Kuo4,2, Christy Pu5, Yiing-Jenq Chou5. 1. Department of Otolaryngology, Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan. 2. Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan. 3. Institute of Hospital and Health Care Management, School of Medicine, National Yang-Ming University, Taipei, Taiwan. 4. Department of Otolaryngology, National Yang-Ming University Hospital, Yilan County, Taiwan. 5. Institute of Public Health, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Abstract
BACKGROUND: Oral cavity cancer is one of the most common head and neck cancers in the world. The purpose of this study was to determine the incidence and risk factors for stroke after surgery in patients with oral cavity cancer with a focus on the effect of neck dissection. METHODS: Data from the Taiwan National Health Insurance Research Database for newly diagnosed oral cavity cancer between January 1, 2005, and December 31, 2007, were included. RESULTS: Neck dissection did not increase the risk of stroke after treatment. Patients with ages older than 44 years, hypertension, diabetes mellitus, coronary artery disease, previous stroke, or postoperative chemoradiotherapy had a significantly higher risk of stroke (p < .05). CONCLUSION: Our data demonstrate that neck dissection does not increase the risk of stroke in patients with oral cavity cancer. Patients have higher risk of stroke after cancer treatment because of their older age, specific comorbidities, and/or type of postoperative treatment.
BACKGROUND: Oral cavity cancer is one of the most common head and neck cancers in the world. The purpose of this study was to determine the incidence and risk factors for stroke after surgery in patients with oral cavity cancer with a focus on the effect of neck dissection. METHODS: Data from the Taiwan National Health Insurance Research Database for newly diagnosed oral cavity cancer between January 1, 2005, and December 31, 2007, were included. RESULTS: Neck dissection did not increase the risk of stroke after treatment. Patients with ages older than 44 years, hypertension, diabetes mellitus, coronary artery disease, previous stroke, or postoperative chemoradiotherapy had a significantly higher risk of stroke (p < .05). CONCLUSION: Our data demonstrate that neck dissection does not increase the risk of stroke in patients with oral cavity cancer. Patients have higher risk of stroke after cancer treatment because of their older age, specific comorbidities, and/or type of postoperative treatment.
Authors: Daniel Addison; Patrick R Lawler; Hamed Emami; Sumbal A Janjua; Pedro V Staziaki; Travis R Hallett; Orla Hennessy; Hang Lee; Bálint Szilveszter; Michael Lu; Negar Mousavi; Matthew G Nayor; Francesca N Delling; Javier M Romero; Lori J Wirth; Annie W Chan; Udo Hoffmann; Tomas G Neilan Journal: J Stroke Date: 2018-01-31 Impact factor: 6.967