Literature DB >> 27438622

Congenital Glioblastoma: Lessons Learned from a Rare Case with Unusual Presentation.

Atef Ben Nsir1, Mehdi Darmoul, Rym Hadhri, Nejib Hattab.   

Abstract

Congenital glioblastomas are uncommon tumors of infancy with unique molecular features and usually better prognosis compared to their pediatric and adult counterparts. A 15-day old newborn harboring a congenital glioblastoma undiagnosed at pregnancy presented to our emergencies with rapid neurological deterioration. Radiological investigations revealed an 8 by 9 cm space occupying and enhancing lesion in the left temporoparietooccipital region with intratumoral hemorrhage. The patient was immediately transferred to the operative theater and was operated in a poor condition. Unfortunately he showed no improvement post-operatively and died within two days in the intensive care unit. As such presentation is unique; we present the case and review the relevant literature concerning the potential pitfalls in diagnosis, management strategies and improvements in outcome.

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Year:  2017        PMID: 27438622     DOI: 10.5137/1019-5149.JTN.13047-14.3

Source DB:  PubMed          Journal:  Turk Neurosurg        ISSN: 1019-5149            Impact factor:   1.003


  1 in total

1.  Targetable molecular alterations in congenital glioblastoma.

Authors:  Ahmed Gilani; Andrew Donson; Kurtis D Davies; Susan L Whiteway; Jessica Lake; John DeSisto; Lindsey Hoffman; Nicholas K Foreman; B K Kleinschmidt-DeMasters; Adam L Green
Journal:  J Neurooncol       Date:  2019-12-24       Impact factor: 4.130

  1 in total

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