Literature DB >> 27438211

Ulcerations due to methotrexate toxicity in a psoriasis patient.

Claudia Fernanda Dias Souza1, Olga Milena Zarco Suarez1, Talita Fonseca Medeiros da Silva1, Ana Carolina Lourenço Araújo Gorenstein1, Leonardo Pereira Quintella1,2, João Carlos Regazzi Avelleira1.   

Abstract

Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription.

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Year:  2016        PMID： 27438211      PMCID： PMC4938288          DOI： 10.1590/abd1806-4841.20163960

Source DB:  PubMed          Journal:  An Bras Dermatol        ISSN： 0365-0596            Impact factor:   1.896


  8 in total

Review 1.  [Acute methotrexate toxicity in psoriasis].

Authors:  A Arévalo-López
Journal:  Gac Med Mex       Date:  1999 Sep-Oct       Impact factor: 0.302

2.  Focal skin toxicity related to methotrexate sparing psoriatic plaques.

Authors:  Teresa Truchuelo; Javier Alcántara; Carmen Moreno; Sergio Vano-Galván; Pedro Jaén
Journal:  Dermatol Online J       Date:  2010-06-15

3.  Acute methotrexate toxicity seen as plaque psoriasis ulceration and necrosis: A diagnostic clue.

Authors:  Julie L Fridlington; Julia W Tripple; Jason S Reichenberg; Clifton S Hall; Dayna G Diven
Journal:  Dermatol Online J       Date:  2011-11-15

4.  A Case of Cutaneous Side Effect of Methotrexate Mimicking Behçet's Disease.

Authors:  Hyun Jae Lee; Soon Kwon Hong; Jong Keun Seo; Deborah Lee; Ho Suk Sung
Journal:  Ann Dermatol       Date:  2011-08-18       Impact factor: 1.444

Review 5.  Psoriasis treatment: traditional therapy.

Authors:  M Lebwohl; P T Ting; J Y M Koo
Journal:  Ann Rheum Dis       Date:  2005-03       Impact factor: 19.103

Review 6.  Erosion of psoriatic plaques: an early sign of methotrexate toxicity.

Authors:  H P Pearce; B B Wilson
Journal:  J Am Acad Dermatol       Date:  1996-11       Impact factor: 11.527

7.  Methotrexate toxicity presenting as ulceration of psoriatic plaques: a report of two cases.

Authors:  Kishan Kumar Agarwal; Amiya Kumar Nath; Devinder Mohan Thappa
Journal:  Indian J Dermatol Venereol Leprol       Date:  2008 Sep-Oct       Impact factor: 2.545

8.  Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. An analysis of ten cases.

Authors:  P J Kerstens; A M Boerbooms; M E Jeurissen; J H Fast; K J Assmann; L B van de Putte
Journal:  J Rheumatol       Date:  1992-06       Impact factor: 4.666
  8 in total
  2 in total

1.  Accidental Chronic Poisoning with Methotrexate; Report of Two Cases.

Authors:  Reza Bidaki; Mojgan Kian; Hamid Owliaey; Mojtaba Babaei Zarch; Masoud Feysal
Journal:  Emerg (Tehran)       Date:  2017-05-21

2.  Methotrexate Cutaneous Toxicity following a Single Dose of 10 mg in a Case of Chronic Plaque Psoriasis: A Possible Idiosyncratic Reaction.

Authors:  Aastha Gupta; Kabir Sardana; Minakshi Bhardwaj; Ajeet Singh
Journal:  Indian Dermatol Online J       Date:  2018 Sep-Oct
  2 in total

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