Literature DB >> 27437366

The Mouthwash War - Chlorhexidine vs. Herbal Mouth Rinses: A Meta-Analysis.

Sunayana Manipal1, Sajjid Hussain2, Umesh Wadgave3, Prabu Duraiswamy4, K Ravi5.   

Abstract

INTRODUCTION: Mouthwashes are often prescribed in dentistry for prevention and treatment of several oral conditions. In the recent times the use of naturally occurring products what is otherwise known as grandmothers remedy are used on a large scale. This has now called for a newer age of mouth washes but is the new age mouth washes at par with the gold standard or even better than them this study investigates. AIM: The aim of the present study was to compare the effect of two broad categories of mouth washes namely chlorhexidine and herbal mouth washes.
MATERIALS AND METHODS: Eleven randomized control studies were pooled in for the meta-analysis. The search was done from the Pub Med Central listed studies with the use keywords with Boolean operators (chlorhexidine, herbal, mouth wash, randomized control trials). The fixed effects model was used for analysis.
RESULTS: This meta-analysis brings to light, the fact that a wide range of newer herbal products are now available. As with a plethora of herbal mouthwashes available it is the need of the hour to validate their potential use and recommendation. This study found that only two studies favor the use of herbal products and four studies favor the use of chlorhexidine, of the 11 studies that were analyzed.
CONCLUSION: More studies are required under well controlled circumstances to prove that herbal products can equate or replace the 'gold standard' chlorhexidine. Herbal products are heterogeneous in nature, their use should be advised only with more scientific proof.

Entities:  

Keywords:  Chlorhexidine; Plaque index; Randomized control trials

Year:  2016        PMID: 27437366      PMCID: PMC4948542          DOI: 10.7860/JCDR/2016/16578.7815

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  21 in total

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Authors:  Arie Shifman; Shmuel Orenbuch; Mel Rosenberg
Journal:  Isr Med Assoc J       Date:  2002-10       Impact factor: 0.892

2.  PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION.

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Journal:  Acta Odontol Scand       Date:  1964-02       Impact factor: 2.331

3.  The inhibiting effect of aqueous Azadirachta indica (Neem) extract upon bacterial properties influencing in vitro plaque formation.

Authors:  L E Wolinsky; S Mania; S Nachnani; S Ling
Journal:  J Dent Res       Date:  1996-02       Impact factor: 6.116

4.  Chlorhexidine as a denture disinfectant in the treatment of denture stomatitis.

Authors:  E Budtz-Jörgensen; H Löe
Journal:  Scand J Dent Res       Date:  1972

5.  The history of oral hygiene products: how far have we come in 6000 years?

Authors:  S L Fischman
Journal:  Periodontol 2000       Date:  1997-10       Impact factor: 7.589

6.  To evaluate the antigingivitis and antipalque effect of an Azadirachta indica (neem) mouthrinse on plaque induced gingivitis: A double-blind, randomized, controlled trial.

Authors:  Anirban Chatterjee; Mini Saluja; Nidhi Singh; Abhishek Kandwal
Journal:  J Indian Soc Periodontol       Date:  2011-10

7.  Comparative clinical and microbiological efficacy of mouthwashes containing 0.2% and 0.12% chlorhexidine.

Authors:  S K Rath; Munishwar Singh
Journal:  Dent Res J (Isfahan)       Date:  2013-05

8.  Effect of two herbal mouthwashes on gingival health of school children.

Authors:  Ratika Sharma; Mamata Hebbal; Anil V Ankola; Vikneshan Murugaboopathy; Sindhu Jayasimha Shetty
Journal:  J Tradit Complement Med       Date:  2014-10

9.  Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent.

Authors:  Mayur Sudhakar Khairnar; Babita Pawar; Pramod Parashram Marawar; Ameet Mani
Journal:  J Indian Soc Periodontol       Date:  2013-11

10.  A randomized controlled clinical trial of Ocimum sanctum and chlorhexidine mouthwash on dental plaque and gingival inflammation.

Authors:  Devanand Gupta; Dara John Bhaskar; Rajendra Kumar Gupta; Bushra Karim; Ankita Jain; Rajeshwar Singh; Wahaja Karim
Journal:  J Ayurveda Integr Med       Date:  2014-04
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  9 in total

Review 1.  Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare providers.

Authors:  Sumanth Kumbargere Nagraj; Prashanti Eachempati; Martha Paisi; Mona Nasser; Gowri Sivaramakrishnan; Tony Francis; Jos H Verbeek
Journal:  Cochrane Database Syst Rev       Date:  2022-08-22

Review 2.  Evidence on the Use of Mouthwash for the Control of Supragingival Biofilm and Its Potential Adverse Effects.

Authors:  Shoji Takenaka; Maki Sotozono; Naoto Ohkura; Yuichiro Noiri
Journal:  Antibiotics (Basel)       Date:  2022-05-28

3.  Clinical and microbiological effects of 1% Matricaria chamomilla mouth rinse on chronic periodontitis: A double-blind randomized placebo controlled trial.

Authors:  Ashish Agarwal; Bharti Chaudhary
Journal:  J Indian Soc Periodontol       Date:  2020-06-05

4.  Chlorhexidine residues in sludge from municipal wastewater treatment plants: analytical determination and toxicity evaluation.

Authors:  Miguel Cobo Golpe; Gabriela Castro; Maria Ramil; Rafael Cela; Ysabel Santos; Isaac Rodríguez
Journal:  Anal Bioanal Chem       Date:  2022-07-13       Impact factor: 4.478

5.  Efficacy of Ayurvedic drugs as compared to chlorhexidine in management of chronic periodontitis: A randomized controlled clinical study.

Authors:  Neelam Mittal; Vinod Kumar Joshi; Ratan Kumar Srivastava; Shri Prakash Singh
Journal:  J Indian Soc Periodontol       Date:  2018 Jan-Feb

6.  Efficacy of an All-Natural Polyherbal Mouthwash in Patients With Periodontitis: A Single-Blind Randomized Controlled Trial.

Authors:  Scilla Sparabombe; Riccardo Monterubbianesi; Vincenzo Tosco; Giulia Orilisi; Andrell Hosein; Luigi Ferrante; Angelo Putignano; Giovanna Orsini
Journal:  Front Physiol       Date:  2019-05-22       Impact factor: 4.566

Review 7.  Adverse events associated with home use of mouthrinses: a systematic review.

Authors:  Gianluca M Tartaglia; Santosh Kumar Tadakamadla; Stephen Thaddeus Connelly; Chiarella Sforza; Conchita Martín
Journal:  Ther Adv Drug Saf       Date:  2019-09-23

8.  Cannabinoids infused mouthwash products are as effective as chlorhexidine on inhibition of total-culturable bacterial content in dental plaque samples.

Authors:  Kumar Vasudevan; Veronica Stahl
Journal:  J Cannabis Res       Date:  2020-06-23

9.  Comparative evaluation of the efficacy of a herbal mouthwash and chlorhexidine mouthwash on select periodontal pathogens: An in vitro and ex vivo study.

Authors:  Multazim Muradkhan Pathan; Kishore Gajanan Bhat; Vinayak Mahableshwar Joshi
Journal:  J Indian Soc Periodontol       Date:  2017 Jul-Aug
  9 in total

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