| Literature DB >> 27437288 |
Mohan Varadanayakanahalli Bhojaraja1, Pradeep Kumar Reddy Kistampally2, Karthik S Udupa3, Joseph Thomas4.
Abstract
Subcutaneous Panniculitis like T cell Lymphoma (SPTCL) is an uncommon variant and poorly differentiated type of cutaneous T cell lymphoma. Here we describe the case of a 19-year-old female who presented with swelling of left half of the face with no regional lymphadenopathy and hepatosplenomegaly which was initially misdiagnosed as a benign cutaneous condition by various practitioners. Histopathological examination revealed diffuse infiltration of subcutaneous plane by small to medium sized atypical lymphocytes. Immunohistochemistry showed CD3, CD8 and βF-1 positivity; CD20, CD56, Epstein Barr Virus (EBV) and TCR-δ negativity. Clinical profile, histopathology and immunohistochemical analysis yielded a diagnosis of SPTCL. Thus cases with atypical and nonresolving dermatological lesions should raise a suspicion of SPTCL as diagnosis against other benign conditions.Entities:
Keywords: Atypical lymphocytes; Cutaneous condition; Face; Non resolving
Year: 2016 PMID: 27437288 PMCID: PMC4948464 DOI: 10.7860/JCDR/2016/18458.7824
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X