| Literature DB >> 27436330 |
Abstract
The inappropriate phosphorus retention observed in chronic kidney disease is central to the pathophysiology of mineral and bone disorders observed in these patients. Subsequent derangements in serum fibroblast growth factor 23, parathyroid hormone, and calcitriol concentrations play contributory roles. Therapeutic intervention involves dietary phosphorus restriction and intestinal phosphate binders in order to correct phosphorus retention and maintain normocalcemia. Additional therapies may be considered to normalize serum fibroblast growth factor 23 and parathyroid hormone.Entities:
Keywords: Fibroblast growth factor 23; Hyperphosphatemia; Renal osteodystrophy; Renal secondary hyperparathyroidism
Mesh:
Year: 2016 PMID: 27436330 DOI: 10.1016/j.cvsm.2016.06.003
Source DB: PubMed Journal: Vet Clin North Am Small Anim Pract ISSN: 0195-5616 Impact factor: 2.093