S Siebelmann1,2, B Bachmann3, A Lappas3, T Dietlein3, M Hermann3, S Roters3, C Cursiefen3, P Steven3,4. 1. Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland. Sebastian.Siebelmann@uk-koeln.de. 2. Cluster of Excellence: Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Köln, Deutschland. Sebastian.Siebelmann@uk-koeln.de. 3. Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland. 4. Cluster of Excellence: Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Köln, Deutschland.
Abstract
BACKGROUND: Optical coherence tomography (OCT) is the clinical gold standard for anterior and posterior segment imaging. Since OCT devices have been integrated into surgical microscopes, this technique is also available intraoperatively in anterior segment surgery. OCT is well established in imaging very thin or transparent structures as they appear in corneal or glaucoma surgery. Therefore, intraoperative OCT can deliver important information for the surgeon which is superior to the normal surgical microscope. OBJECTIVES: In the present work, an overview about the opportunities of intraoperative OCT in cornea and glaucoma surgery are presented. MATERIAL AND METHODS: The recent literature (PubMed) and our own experience at the Center for Ophthalmology, University Hospital of Cologne are analysed. RESULTS: Intraoperative OCT enables real-time imaging during corneal and glaucoma surgery. Several clinical studies exist, indicating its benefit, e. g. in DMEK, DALK, DSAEK, Boston Keratoprosthesis, canaloplasty or trabectome surgery. Several structures, not visible in the surgical microscope, can be visualized using intraoperative OCT. CONCLUSIONS: As a real-time and high-resolution imaging device, intraoperative online OCT delivers additional information in glaucoma and corneal surgery, compared to the normal operating microscope. Nonetheless one of the main problems is the shadowing produced by surgical instruments. Today the main limitation is the lack of randomized-controlled clinical trials, evaluating the benefit of microscope-integrated intraoperative OCT, compared to the microscope.
BACKGROUND: Optical coherence tomography (OCT) is the clinical gold standard for anterior and posterior segment imaging. Since OCT devices have been integrated into surgical microscopes, this technique is also available intraoperatively in anterior segment surgery. OCT is well established in imaging very thin or transparent structures as they appear in corneal or glaucoma surgery. Therefore, intraoperative OCT can deliver important information for the surgeon which is superior to the normal surgical microscope. OBJECTIVES: In the present work, an overview about the opportunities of intraoperative OCT in cornea and glaucoma surgery are presented. MATERIAL AND METHODS: The recent literature (PubMed) and our own experience at the Center for Ophthalmology, University Hospital of Cologne are analysed. RESULTS: Intraoperative OCT enables real-time imaging during corneal and glaucoma surgery. Several clinical studies exist, indicating its benefit, e. g. in DMEK, DALK, DSAEK, Boston Keratoprosthesis, canaloplasty or trabectome surgery. Several structures, not visible in the surgical microscope, can be visualized using intraoperative OCT. CONCLUSIONS: As a real-time and high-resolution imaging device, intraoperative online OCT delivers additional information in glaucoma and corneal surgery, compared to the normal operating microscope. Nonetheless one of the main problems is the shadowing produced by surgical instruments. Today the main limitation is the lack of randomized-controlled clinical trials, evaluating the benefit of microscope-integrated intraoperative OCT, compared to the microscope.
Authors: Neel D Pasricha; Christine Shieh; Oscar M Carrasco-Zevallos; Brenton Keller; Joseph A Izatt; Cynthia A Toth; Anthony N Kuo Journal: Cornea Date: 2015-12 Impact factor: 2.651
Authors: Philipp Steven; Carolin Le Blanc; Eva Lankenau; Marc Krug; Stefan Oelckers; Ludwig M Heindl; Uta Gehlsen; Gereon Huettmann; Claus Cursiefen Journal: Br J Ophthalmol Date: 2014-07 Impact factor: 4.638
Authors: M Matthaei; S Schrittenlocher; D Hos; S Siebelmann; F Bucher; F Schaub; R Hoerster; R Siggel; S Roters; L M Heindl; B Bachmann; C Cursiefen Journal: Ophthalmologe Date: 2019-03 Impact factor: 1.059
Authors: Matteo Mario Carlà; Francesco Boselli; Federico Giannuzzi; Gloria Gambini; Tomaso Caporossi; Umberto De Vico; Luigi Mosca; Laura Guccione; Antonio Baldascino; Clara Rizzo; Raphael Kilian; Stanislao Rizzo Journal: Diagnostics (Basel) Date: 2022-03-17