| Literature DB >> 27435519 |
Roger Y Chung1, Stewart W Mercer1,2, Benjamin H K Yip1, Stephanie W C Chan1, Francisco T T Lai1, Harry H X Wang1,3, Martin C S Wong1, Carmen K M Wong1, Regina W S Sit1, Eng-Kiong Yeoh1, Samuel Y S Wong1.
Abstract
Using data collected from 25,780 Hong Kong citizens in a household survey, this study aimed to investigate the association between having regular source of primary care and hospitalization amongst people with and without multimorbidity (two or more chronic conditions). Potential interaction effects of regular primary care with multimorbidity were also examined. Results revealed a significant association between having regular source of primary care from General Practitioners and reduced hospitalization amongst respondents with multimorbidity (RR = 0.772; 95% CI = 0.667-0.894), adjusting for other potential confounding factors (i.e., socio-demographic factors and medical insurance and benefits). In contrast, having regular Specialist care was significantly associated with increased risk of hospitalization among both people with multimorbidity (RR = 1.619; 95% CI = 1.256-2.087) and without multimorbidity (RR = 1.981; 95% CI = 1.246-3.149), adjusting for potential confounders. A dose-response relationship between the number of chronic diseases and hospitalization was also observed, regardless of whether participants had regular source of primary care or not; relative risks and predicted probabilities for hospitalization were generally greater for those without regular source of primary care. Further studies are warranted to explore the role of healthcare system, informatics, organizational and practice-related factors on healthcare and functional outcomes.Entities:
Mesh:
Year: 2016 PMID: 27435519 PMCID: PMC4951721 DOI: 10.1038/srep29758
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.379
Socio-demographic characteristics of the study population (aged 15 or above).
| Variables | No. of respondents (N, %) |
|---|---|
| 25780 (100%) | |
| Sex | |
| Male | 12316 (47.8%) |
| Female | 13464 (52.2%) |
| Age (years) | |
| 15–24 | 3967 (15.4%) |
| 25–34 | 3973 (15.4%) |
| 35–44 | 4383 (17.0%) |
| 45–54 | 5317 (20.6%) |
| 55–64 | 3936 (15.3%) |
| 65 or above | 4204 (16.3%) |
| Marital status | |
| Single | 8534 (33.1%) |
| Married | 14556 (56.5%) |
| Divorced/Separated | 938 (3.6%) |
| Widowed | 1752 (6.8%) |
| Highest education level achieved | |
| Kindergarten or below | 1460 (5.7%) |
| Primary | 4573 (17.7%) |
| Secondary | 15157 (58.8%) |
| Tertiary or above | 4590 (17.8%) |
| Migrant status | |
| Born in Hong Kong | 17235 (66.9%) |
| Mainland China/Macau (<7 years) | 807 (3.1%) |
| Mainland China/Macau (≥7 years) | 7065 (27.4%) |
| Others (<7 years) | 155 (0.6%) |
| Others (≥7 years) | 518 (2.0%) |
| Employed | |
| Yes | 14161 (54.9%) |
| No | 11619 (45.1%) |
| Average monthly household income ($HK; $1US = $7.8HK) | |
| <10,000 | 4372 (17.0%) |
| 10,000–19,999 | 6179 (24.0%) |
| 20,000–29,999 | 5638 (21.9%) |
| 30,000–39,999 | 3856 (15.0%) |
| 40,000–49,999 | 2259 (8.8%) |
| >=50000 | 3476 (13.5%) |
| Medical insurance & benefits | |
| Yes | 11985 (46.5%) |
| No | 13795 (53.5%) |
| Chronic disease | |
| 0 | 17905 (69.5%) |
| 1 | 4406 (17.1%) |
| 2 | 1859 (7.2%) |
| 3 or more | 1610 (6.2%) |
| Regular source of primary care | |
| No | 16998 (65.9%) |
| General Practitioner | 7895 (30.6%) |
| Family Physician | 715 (2.8%) |
| Other Specialists | 172 (0.7%) |
| No. of hospital admissions | |
| 0 | 24339 (94.4%) |
| 1 | 1101 (4.3%) |
| 2 or more | 340 (1.3%) |
Relative risks with 95% confidence intervals (95% CI) of factors associated with hospital admission in the past 12 months among age 15 or above, stratified by (a) those without multimorbidity (No or 1 chronic disease only) and (b) those with multimorbidity (2 or more chronic diseases) using generalized estimating equations based on negative binomial regression.
| Variables | (a) Without multimorbidity | (b) With multimorbidity | ||
|---|---|---|---|---|
| RR | 95% CI | RR | 95% CI | |
| Sex | ||||
| Female | 1.000 | 1.000 | ||
| Male | 0.959 | (0.856–1.075) | 1.461 | (1.286–1.660)++ |
| Age | ||||
| 15–24 | 1.000 | 1.000 | ||
| 25–34 | 1.721 | (1.274–2.324)++ | 0.713 | (0.323–1.572) |
| 35–44 | 1.428 | (1.035–1.972)+ | 0.621 | (0.330–1.169) |
| 45–54 | 1.468 | (1.063–2.028)+ | 1.048 | (0.630–1.742) |
| 55–64 | 1.587 | (1.138–2.213)+ | 0.922 | (0.559–1.519) |
| 65 or above | 2.575 | (1.837–3.610)++ | 0.746 | (0.449–1.240) |
| Marital Status | ||||
| Single | 1.000 | 1.000 | ||
| Married | 1.996 | (1.624–2.453)++ | 0.917 | (0.706–1.191) |
| Divorced/Separated | 4.107 | (3.150–5.355)++ | 0.941 | (0.654–1.352) |
| Widowed | 2.173 | (1.627–2.903)++ | 1.058 | (0.791–1.416) |
| Educational Attainment | ||||
| Kindergarten or below | 1.000 | 1.000 | ||
| Primary | 0.927 | (0.741–1.160) | 0.835 | (0.716–0.974)+ |
| Secondary | 0.783 | (0.620–0.989)+ | 0.717 | (0.597–0.860)++ |
| Tertiary or above | 1.065 | (0.816–1.389) | 0.792 | (0.608–1.031) |
| Migrant Status | ||||
| Born in Hong Kong | 1.000 | 1.000 | ||
| Mainland China/Macau (≥7 years) | 1.224 | (1.081–1.386)++ | 1.123 | (0.985–1.279) |
| Mainland China/Macau (<7 years) | 1.459 | (1.110–1.917)+ | 1.578 | (0.926–2.688) |
| Others (≥7 years) | 1.285 | (0.925–1.786) | 1.214 | (0.845–1.746) |
| Others (<7 years) | 1.816 | (1.113–2.963)+ | NA (n = 3) | |
| Employment Status | ||||
| Employed | 1.000 | 1.000 | ||
| Non-employment | 1.361 | (1.183–1.566)++ | 2.033 | (1.636–2.528)++ |
| Household Income | ||||
| <10,000 | 1.000 | 1.000 | ||
| 10,000–19,999 | 1.275 | (1.080–1.504)+ | 1.166 | (1.002–1.356)+ |
| 20,000–29,999 | 0.983 | (0.815–1.185) | 1.138 | (0.946–1.368) |
| 30,000–39,999 | 0.830 | (0.665–1.036) | 1.117 | (0.903–1.382) |
| 40,000–49,999 | 0.947 | (0.739–1.215) | 1.054 | (0.779–1.424) |
| >=50000 | 0.847 | (0.673–1.067) | 1.193 | (0.916–1.553) |
| Medical benefits and insurance | ||||
| Not insured | 1.000 | 1.000 | ||
| Insured | 1.635 | (1.438–1.859)++ | 0.960 | (0.809–1.139) |
| Regular Source of Primary Care | ||||
| No | 1.000 | 1.000 | ||
| General Practitioner | 0.963 | (0.851–1.090) | 0.772 | (0.667–0.894)++ |
| Family Physician | 0.833 | (0.570–1.219) | 0.997 | (0.736–1.351) |
| Other Specialists | 1.981 | (1.246–3.149)+ | 1.619 | (1.256–2.087)++ |
+p < 0.05; ++p < 0.001.
*Reference category.
Negative Binomial regression analysis of factors associated with hospital admission in the past 12 months among age 15 or above, with interaction of regular source of primary care and number of chronic diseases.
| Combination | RR (95%CI) |
|---|---|
| No regular source of primary care | |
| No chronic disease | 1.00 |
| 1 chronic disease | 3.591 (3.134–4.114)++ |
| 2 chronic diseases | 4.147 (3.536–4.864)++ |
| 3 or more chronic diseases | 5.668 (4.868–6.599)++ |
| Regular source of primary care (from GP) | |
| No chronic disease | 1.210 (1.023–1.432)+ |
| 1 chronic disease | 2.553 (2.129–3.062)++ |
| 2 chronic diseases | 2.862 (2.264–3.617)++ |
| 3 or more chronic diseases | 4.424 (3.627–5.396)++ |
| Regular source of primary care (from Family Physician) | |
| No chronic disease | 1.127 (0.684–1.856) |
| 1 chronic disease | 1.837 (1.035–3.26)+ |
| 2 chronic diseases | 3.133 (1.741–5.638)++ |
| 3 or more chronic diseases | 5.589 (3.917–7.974)++ |
| Regular source of care (other specialists) | |
| No chronic disease | 2.304 (0.895–5.933) |
| 1 chronic disease | 4.457 (2.601–7.639)++ |
| 2 chronic diseases | 5.840 (3.678–9.272)++ |
| 3 or more chronic diseases | 9.682 (7.161–13.092)++ |
Figures are relative risks (95% confidence intervals). +p < 0.05. ++p < 0.001.
*Reference category: no regular source of primary care and no chronic disease.
Figure 1Predicted probability of hospital admissions by number of chronic diseases (0, 1, 2 and 3 or more) among patients aged 15 or above.
Circles indicate the mean values, and error bars indicate 95% confidence intervals.