Literature DB >> 2743480

The screening of Chinese crude drugs for Ca2+ antagonist activity: identification of active principles from the aerial part of Pogostemon cablin and the fruits of Prunus mume.

K Ichikawa, T Kinoshita, U Sankawa.   

Abstract

Hot aqueous extracts of 134 Chinese crude drugs were subjected to screening for inhibitory activity on K+ contracture of guinea pig taenia coli, and significant activity was observed in 17 crude drugs. Chemical investigations of two crude drugs, Kakko and Ubai, which originate from Pogostemon cablin and Prunus mume, respectively, were undertaken, and patchouli alcohol (I) and 5-(hydroxymethyl)-2-furaldehyde (II) were identified as their active principles, respectively.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2743480     DOI： 10.1248/cpb.37.345

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  6 in total

1.  A pharmacokinetic study of patchouli alcohol after a single oral administration of patchouli alcohol or patchouli oil in rats.

Authors:  Ruoqi Zhang; Peiao Yan; Yunxia Li; Liang Xiong; Xiaohong Gong; Cheng Peng
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2015-03-10       Impact factor: 2.441

Review 2.  Potential benefits of patchouli alcohol in prevention of human diseases: A mechanistic review.

Authors:  Hee-Seop Lee; Jihye Lee; Dmitriy Smolensky; Seong-Ho Lee
Journal:  Int Immunopharmacol       Date:  2020-10-08       Impact factor: 4.932

3.  Analgesic and Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin.

Authors:  Tsung-Chun Lu; Jung-Chun Liao; Tai-Hung Huang; Ying-Chih Lin; Chia-Yu Liu; Yung-Jia Chiu; Wen-Huang Peng
Journal:  Evid Based Complement Alternat Med       Date:  2011-02-14       Impact factor: 2.629

4.  Three statistical experimental designs for enhancing yield of active compounds from herbal medicines and anti-motion sickness bioactivity.

Authors:  Yan Chen; Cuiping Zhang; Mei Zhang; Xiaobing Fu
Journal:  Pharmacogn Mag       Date:  2015 Jul-Sep       Impact factor: 1.085

5.  Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome.

Authors:  Tian-Ran Zhou; Jing-Jing Huang; Zi-Tong Huang; Hong-Ying Cao; Bo Tan
Journal:  World J Gastroenterol       Date:  2018-02-14       Impact factor: 5.742

6.  Relaxation Effect of Patchouli Alcohol in Rat Corpus Cavernous and Its Underlying Mechanisms.

Authors:  Fangjun Chen; Yifei Xu; Jing Wang; Xufeng Yang; Hongying Cao; Ping Huang
Journal:  Evid Based Complement Alternat Med       Date:  2020-02-28       Impact factor: 2.629
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.