Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The Itch to degrade ROR-γt.

Literature DB >> 27434002

The Itch to degrade ROR-γt.

Sascha Rutz¹, Wenjun Ouyang².

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2016 PMID： 27434002 DOI： 10.1038/ni.3516

Source DB: PubMed Journal: Nat Immunol ISSN： 1529-2908 Impact factor: 25.606

× No keyword cloud information.

13 in total

Review 1. Emerging cytokine networks in colorectal cancer.

Authors: Nathan R West; Sarah McCuaig; Fanny Franchini; Fiona Powrie
Journal: Nat Rev Immunol Date: 2015-09-11 Impact factor: 53.106

Review 2. Multifaceted role of the ubiquitin ligase Itch in immune regulation.

Authors: K Venuprasad; Minghui Zeng; Scott L Baughan; Ramin Massoumi
Journal: Immunol Cell Biol Date: 2015-01-13 Impact factor: 5.126

Review 3. The ubiquitin system in immune regulation.

Authors: Yoon Park; Hyung-seung Jin; Daisuke Aki; Jeeho Lee; Yun-Cai Liu
Journal: Adv Immunol Date: 2014 Impact factor: 3.543

4. Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt.

Authors: Jing Yang; Peng Xu; Lei Han; Zhixiang Guo; Xiuwen Wang; Zuojia Chen; Jia Nie; Shuying Yin; Miranda Piccioni; Andy Tsun; Ling Lv; Shenglin Ge; Bin Li
Journal: J Immunol Date: 2015-03-27 Impact factor: 5.422

5. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination.

Authors: Mahesh Kathania; Prashant Khare; Minghui Zeng; Brandi Cantarel; Haiying Zhang; Hideki Ueno; K Venuprasad
Journal: Nat Immunol Date: 2016-06-20 Impact factor: 25.606

6. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Authors: Sascha Rutz; Nobuhiko Kayagaki; Qui T Phung; Celine Eidenschenk; Rajkumar Noubade; Xiaoting Wang; Justin Lesch; Rongze Lu; Kim Newton; Oscar W Huang; Andrea G Cochran; Mark Vasser; Benjamin P Fauber; Jason DeVoss; Joshua Webster; Lauri Diehl; Zora Modrusan; Donald S Kirkpatrick; Jennie R Lill; Wenjun Ouyang; Vishva M Dixit
Journal: Nature Date: 2014-12-03 Impact factor: 49.962

Review 7. Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function.

Authors: Awo A K Layman; Paula M Oliver
Journal: J Immunol Date: 2016-05-15 Impact factor: 5.422

8. TRAF5-mediated Lys-63-linked Polyubiquitination Plays an Essential Role in Positive Regulation of RORγt in Promoting IL-17A Expression.

Authors: Xiuwen Wang; Jing Yang; Lei Han; Kaixia Zhao; Qingsi Wu; Liming Bao; Zhiyuan Li; Ling Lv; Bin Li
Journal: J Biol Chem Date: 2015-10-09 Impact factor: 5.157

The Itch to degrade ROR-γt.

Review 1. Emerging cytokine networks in colorectal cancer.

Review 2. Multifaceted role of the ubiquitin ligase Itch in immune regulation.

Review 3. The ubiquitin system in immune regulation.

4. Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt.

5. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination.

6. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Review 7. Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function.

8. TRAF5-mediated Lys-63-linked Polyubiquitination Plays an Essential Role in Positive Regulation of RORγt in Promoting IL-17A Expression.

Review 9. Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

Review 10. Drugging the undruggables: exploring the ubiquitin system for drug development.

Review 1. Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.

2. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2.