Literature DB >> 27432273

Effect of single dose radiation therapy on weight-bearing lameness in dogs with elbow osteoarthritis.

Amy S Kapatkin1, Barbro Nordquist, Tanya C Garcia, Maureen A Griffin, Alain Theon, Sun Kim, Kei Hayashi.   

Abstract

OBJECTIVES: To determine if a single low dose of radiation therapy in dogs with osteoarthritis of the elbow joint was associated with a detectable improvement in their lameness and pain as documented by force platform gait analysis.
METHODS: In this cohort longitudinal observational study, five Labrador Retrievers with lameness due to elbow osteoarthritis that was unresponsive to medical treatment were removed from all non-steroidal anti-inflammatory and analgesic medications. A single treatment of radiation therapy delivering 10 Gray was performed on the affected elbow joint(s). Force platform gait analysis was used to assess the ground reaction forces of a limb affected with elbow osteoarthritis both before and after radiation therapy.
RESULTS: Significant differences occurred in the weight-bearing on an affected limb with elbow osteoarthritis after radiation therapy at weeks six and 14. Change due to treatment was particularly apparent in dogs with unilateral elbow osteoarthritis. CLINICAL SIGNIFICANCE: Administering a single low dose of radiation therapy may have a short-term benefit in dogs with elbow osteoarthritis, which is similar to the evidence supporting the use of radiation therapy in horses with orthopaedic disease.

Entities:  

Keywords:  Elbow; force platform gait analysis; osteoarthritis; radiotherapy

Mesh:

Year:  2016        PMID: 27432273     DOI: 10.3415/VCOT-15-11-0183

Source DB:  PubMed          Journal:  Vet Comp Orthop Traumatol        ISSN: 0932-0814            Impact factor:   1.358


  6 in total

1.  Re-irradiation for osteoarthritis-retrospective analysis of 217 joints.

Authors:  Matthias G Hautmann; Philipp Rechner; Matthias Hipp; Ulrich Neumaier; Felix Steger; Fabian Pohl; Markus Weber; Oliver Kölbl; Christoph Süß
Journal:  Strahlenther Onkol       Date:  2019-07-25       Impact factor: 3.621

2.  Low dose radiation therapy for the treatment of refractory canine osteoarthritis.

Authors:  Daniela B Solis; Monique N Mayer
Journal:  Can Vet J       Date:  2022-08       Impact factor: 1.075

3.  Preclinical Models of Elbow Injury and Pathology.

Authors:  Michael A David; Aaron M Chamberlain; Spencer P Lake
Journal:  Ann Jt       Date:  2021-01-15

4.  Is low dose radiotherapy an effective treatment for Baker's cyst?

Authors:  Matthias G Hautmann; Ernst-Michael Jung; Lukas P Beyer; Christoph Süß; Felix Steger; Markus Weber; Fabian Pohl; Oliver Kölbl; Franz Josef Putz
Journal:  Strahlenther Onkol       Date:  2018-10-30       Impact factor: 3.621

5.  Prospective Clinical Evaluation of Intra-Articular Injection of Tin-117m (117mSn) Radiosynoviorthesis Agent for Management of Naturally Occurring Elbow Osteoarthritis in Dogs: A Pilot Study.

Authors:  Karanvir S Aulakh; Mandi J Lopez; Caleb Hudson; Lorrie Gaschen; Michelle Fabiani; Brian Beale; Frank M Andrews; Chin-Chi Liu; Jimmy Lattimer
Journal:  Vet Med (Auckl)       Date:  2021-06-04

6.  Megavoltage Radiotherapy for the Treatment of Degenerative Joint Disease in Dogs: Results of a Preliminary Experience in an Italian Radiotherapy Centre.

Authors:  Federica Rossi; Simona Cancedda; Vito Ferdinando Leone; Carla Rohrer Bley; Paola Laganga
Journal:  Front Vet Sci       Date:  2018-04-10
  6 in total

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