Xiangui He1, Peiyao Jin, Haidong Zou, Qiangqiang Li, Jiali Jin, Lina Lu, Huijuan Zhao, Jiangnan He, Xun Xu, Mingjin Wang, Jianfeng Zhu. 1. *Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China; †Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China; and ‡Department of School Health, Baoshan Center for Disease Prevention and Control, Shanghai, China.
Abstract
PURPOSE: To explore the characteristics of choroidal thickness (ChT) in Chinese children. METHODS: A total of 144 healthy children, aged 6 years to 12 years old, were enrolled in the study. The ChT of subfovea and peripheral locations 0.5, 1.5, and 2.5 mm away from the fovea were evaluated by enhanced depth imaging optical coherence tomography. The association between subfoveal ChT and systemic, as well as ocular factors, including age, sex, height, weight, body mass index, axial length, refractive error, intraocular pressure, preterm history, and the refractive status of parents were studied. RESULTS: The mean subfoveal ChT was 302 ± 63 μm. In the nasal, superior, and inferior areas, the ChT of locations closer to the fovea was thicker than those farther away from the fovea (all P < 0.05); however, ChT was not significantly different among different locations in the temporal area (P = 0.16). The ChT of the nasal quadrant was significantly thinner than that of other areas (P < 0.01). Subfoveal ChT decreased with age, axial length, preterm history, and increased with height. Sex was not statistically associated with subfoveal ChT. CONCLUSION: In Chinese children, the ChT is thinnest in the nasal quadrant and thicker in central regions than in peripheral areas. The subfoveal ChT independently decreases with age, axial length, preterm history, and increases with height.
PURPOSE: To explore the characteristics of choroidal thickness (ChT) in Chinese children. METHODS: A total of 144 healthy children, aged 6 years to 12 years old, were enrolled in the study. The ChT of subfovea and peripheral locations 0.5, 1.5, and 2.5 mm away from the fovea were evaluated by enhanced depth imaging optical coherence tomography. The association between subfoveal ChT and systemic, as well as ocular factors, including age, sex, height, weight, body mass index, axial length, refractive error, intraocular pressure, preterm history, and the refractive status of parents were studied. RESULTS: The mean subfoveal ChT was 302 ± 63 μm. In the nasal, superior, and inferior areas, the ChT of locations closer to the fovea was thicker than those farther away from the fovea (all P < 0.05); however, ChT was not significantly different among different locations in the temporal area (P = 0.16). The ChT of the nasal quadrant was significantly thinner than that of other areas (P < 0.01). Subfoveal ChT decreased with age, axial length, preterm history, and increased with height. Sex was not statistically associated with subfoveal ChT. CONCLUSION: In Chinese children, the ChT is thinnest in the nasal quadrant and thicker in central regions than in peripheral areas. The subfoveal ChT independently decreases with age, axial length, preterm history, and increases with height.
Authors: Tiziano Ronchetti; Christoph Jud; Peter M Maloca; Selim Orgül; Alina T Giger; Christoph Meier; Hendrik P N Scholl; Rachel Ka Man Chun; Quan Liu; Chi-Ho To; Boris Považay; Philippe C Cattin Journal: PLoS One Date: 2019-06-28 Impact factor: 3.240
Authors: Samantha Sze-Yee Lee; David Alonso-Caneiro; Gareth Lingham; Fred K Chen; Paul G Sanfilippo; Seyhan Yazar; David A Mackey Journal: Invest Ophthalmol Vis Sci Date: 2022-05-02 Impact factor: 4.925
Authors: Hosein Hoseini-Yazdi; Stephen J Vincent; Michael J Collins; Scott A Read; David Alonso-Caneiro Journal: Sci Rep Date: 2019-03-05 Impact factor: 4.379
Authors: Chun On Lee; Xiujuan Zhang; Nan Yuan; Shumin Tang; Li Jia Chen; Carol Y Cheung; Jason C Yam Journal: Sci Rep Date: 2021-07-02 Impact factor: 4.379