Charlotte Chruzander1, Petter Tinghög2, Charlotte Ytterberg1, Lotta Widén Holmqvist3, Kristina Alexanderson4, Jan Hillert5, Sverker Johansson6. 1. Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, SE - 141 83 Stockholm, Sweden; Department of Physiotherapy, Karolinska University Hospital, SE - 141 86 Stockholm, Sweden. 2. Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE - 171 77 Stockholm, Sweden; Red Cross University College, SE - 114 28 Stockholm, Sweden. 3. Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, SE - 141 83 Stockholm, Sweden; Department of Physiotherapy, Karolinska University Hospital, SE - 141 86 Stockholm, Sweden; Division of Neuroscience, Department of Clinical Neuroscience, Karolinska Institutet, SE - 171 77 Stockholm, Sweden. 4. Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE - 171 77 Stockholm, Sweden. 5. Division of Neuroscience, Department of Clinical Neuroscience, Karolinska Institutet, SE - 171 77 Stockholm, Sweden. 6. Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, SE - 141 83 Stockholm, Sweden; Department of Physiotherapy, Karolinska University Hospital, SE - 141 86 Stockholm, Sweden. Electronic address: sverker.johansson@ki.se.
Abstract
BACKGROUND: Even though it is well known that disability due to MS is highly associated with employment status, the long-term longitudinal perspective on sickness absence and disability pension over the MS trajectory is lacking. In addition, further knowledge of risk factors for future disability pension is needed. OBJECTIVES: To explore long-term longitudinal changes in the prevalence of sickness absence and disability pension in people with MS (PwMS), as well as to explore associations between disease-specific factors, contextual factors and functioning, and the outcome of future full-time disability pension. METHODS: A prospective, population-based survival cohort study, with a nine year follow-up, including 114 PwMS was conducted by combining face-to-face collected data and register-based data. RESULTS: The prevalence of full-time disability pension increased from 20% to 50%, however 24% of the PwMS had no disability pension at all at end of follow-up. Sex, age, disease severity and impaired manual dexterity were associated with future full-time disability pension. CONCLUSIONS: The large increase in prevalence of PwMS on full-time disability pension during the MS trajectory, calls for the development and implementation of evidence-based interventions, aiming at keeping PwMS in the work force. Modifiable factors, such as manual dexterity should be targeted in such interventions.
BACKGROUND: Even though it is well known that disability due to MS is highly associated with employment status, the long-term longitudinal perspective on sickness absence and disability pension over the MS trajectory is lacking. In addition, further knowledge of risk factors for future disability pension is needed. OBJECTIVES: To explore long-term longitudinal changes in the prevalence of sickness absence and disability pension in people with MS (PwMS), as well as to explore associations between disease-specific factors, contextual factors and functioning, and the outcome of future full-time disability pension. METHODS: A prospective, population-based survival cohort study, with a nine year follow-up, including 114 PwMS was conducted by combining face-to-face collected data and register-based data. RESULTS: The prevalence of full-time disability pension increased from 20% to 50%, however 24% of the PwMS had no disability pension at all at end of follow-up. Sex, age, disease severity and impaired manual dexterity were associated with future full-time disability pension. CONCLUSIONS: The large increase in prevalence of PwMS on full-time disability pension during the MS trajectory, calls for the development and implementation of evidence-based interventions, aiming at keeping PwMS in the work force. Modifiable factors, such as manual dexterity should be targeted in such interventions.
Authors: Astrid R Bosma; Chantelle Murley; Jenny Aspling; Jan Hillert; Frederieke G Schaafsma; Johannes R Anema; Cécile R L Boot; Kristina Alexanderson; Alejandra Machado; Emilie Friberg Journal: Mult Scler Date: 2021-10-06 Impact factor: 5.855
Authors: Michael Wiberg; Chantelle Murley; Petter Tinghög; Kristina Alexanderson; Edward Palmer; Jan Hillert; Magnus Stenbeck; Emilie Friberg Journal: BMJ Open Date: 2019-07-11 Impact factor: 2.692