| Literature DB >> 27423481 |
Michael P Dwyer1, Kerry M Keertikar2, Lei Chen2, Ling Tong2, Oleg Selyutin2, Anilkumar G Nair2, Wensheng Yu2, Guowei Zhou2, Brian J Lavey2, De-Yi Yang2, Michael Wong2, Seong Heon Kim2, Craig A Coburn2, Stuart B Rosenblum2, Qingbei Zeng2, Yueheng Jiang2, Bandarpalle B Shankar2, Razia Rizvi2, Amin A Nomeir3, Rong Liu4, Sony Agrawal4, Ellen Xia4, Rong Kong4, Ying Zhai4, Paul Ingravallo4, Ernest Asante-Appiah4, Joseph A Kozlowski2.
Abstract
A matched and mixed capping SAR study was conducted on the tetracyclic indole class of HCV NS5A inhibitors to examine the influence of modifications of this region on the overall HCV virologic resistance profiles.Entities:
Keywords: Capping; Hepatitis C; Indole; Infectious diseases; NS5A
Mesh：
Substances：
Year: 2016 PMID： 27423481 DOI： 10.1016/j.bmcl.2016.06.063
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823