J H Lee1, T H Kim1, S H Park1, K Han1,2, S-C Kim1. 1. Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. 2. Biostatistics Collaboration Unit, Gangnam Medical Research Center, Yonsei university College of Medicine, Seoul, Korea.
Abstract
BACKGROUND: Prognostic factors for remission and relapse of bullous pemphigoid (BP) remain uncertain. OBJECTIVE: To evaluate clinical factors associated with remission and relapse in Korean patients with BP. METHODS: A retrospective analysis was conducted of 174 patients diagnosed with BP between 1993 and 2014 at Gangnam Severance Hospital in Seoul, Korea. RESULTS: Of the 174 identified patients, 131 (75.29%) achieved remission after a mean treatment duration of 393.69 days. Prognostic factors for remission were older age (≥70 years) and the absence of an admission history. Of 131 patients who achieved remission, 40 patients (30.53%) experienced relapse after a mean duration of 335.65 days. However, no statistically significant factors were predictive of relapse by multivariate analysis. CONCLUSIONS: This study suggests BP patients who are older and have no admission history tend to achieve remission.
BACKGROUND: Prognostic factors for remission and relapse of bullous pemphigoid (BP) remain uncertain. OBJECTIVE: To evaluate clinical factors associated with remission and relapse in Korean patients with BP. METHODS: A retrospective analysis was conducted of 174 patients diagnosed with BP between 1993 and 2014 at Gangnam Severance Hospital in Seoul, Korea. RESULTS: Of the 174 identified patients, 131 (75.29%) achieved remission after a mean treatment duration of 393.69 days. Prognostic factors for remission were older age (≥70 years) and the absence of an admission history. Of 131 patients who achieved remission, 40 patients (30.53%) experienced relapse after a mean duration of 335.65 days. However, no statistically significant factors were predictive of relapse by multivariate analysis. CONCLUSIONS: This study suggests BP patients who are older and have no admission history tend to achieve remission.