Literature DB >> 27421993

Access to treatment for hepatitis C virus infection: time to put patients first.

Brian R Edlin1.   

Abstract

Sound health policy puts patients first. Antiviral regimens approved in 2014 revolutionised treatment of hepatitis C virus (HCV) infection. Most patients can now be cured. These new regimens, however, were priced at US$83 320-150 000 for a 3-month course. Public and private payers in the USA responded by limiting coverage to patients with advanced fibrosis or cirrhosis, keeping the drugs from being used to prevent those stages. These restrictions defy medical guidelines, lack scientific justification, and undermine public health efforts to stem transmission. Instead of reducing barriers to care, the system has erected new ones. As drug makers and payers battle over billions of dollars, the needs of patients have been cast aside. Physicians and governments have a duty to make sure health policy is driven by the needs of patients and public health. In this Personal View, I call upon these groups to lead the creation of a national consensus among all stakeholders that will allow the advances in therapeutics for HCV infection to be put to work to end the epidemic.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID: 27421993     DOI: 10.1016/S1473-3099(16)30005-6

Source DB:  PubMed          Journal:  Lancet Infect Dis        ISSN: 1473-3099            Impact factor:   25.071


  27 in total

1.  Monitoring the hepatitis C care cascade using administrative claims data.

Authors:  Cheryl Isenhour; Susan Hariri; Claudia Vellozzi
Journal:  Am J Manag Care       Date:  2018-05       Impact factor: 2.229

2.  Medicaid Reimbursement for Oral Direct Antiviral Agents for the Treatment of Chronic Hepatitis C.

Authors:  Kohtaro Ooka; James J Connolly; Joseph K Lim
Journal:  Am J Gastroenterol       Date:  2017-04-04       Impact factor: 10.864

3.  The renin angiotensin system in liver and lung: impact and therapeutic potential in organ fibrosis.

Authors:  Amal Abdul-Hafez; Tarek Mohamed; Hanan Omar; Mohamed Shemis; Bruce D Uhal
Journal:  J Lung Pulm Respir Res       Date:  2018-02-27

4.  Patient engagement and study design of PROP UP: A multi-site patient-centered prospective observational study of patients undergoing hepatitis C treatment.

Authors:  Donna M Evon; Carol E Golin; Paul Stewart; Michael W Fried; Shani Alston; Bryce Reeve; Anna S Lok; Richard K Sterling; Joseph K Lim; Nancy Reau; Souvik Sarkar; David R Nelson; K R Reddy; Adrian M Di Bisceglie
Journal:  Contemp Clin Trials       Date:  2017-03-22       Impact factor: 2.226

5.  Barriers to Treatment Access for Chronic Hepatitis C Virus Infection: A Case Series.

Authors:  Alexander J Millman; Boatemaa Ntiri-Reid; Risha Irvin; Maggie H Kaufmann; Andrew Aronsohn; Jeffrey S Duchin; John D Scott; Claudia Vellozzi
Journal:  Top Antivir Med       Date:  2017 Jul/Aug

6.  Hepatitis C: Review of the Epidemiology, Clinical Care, and Continued Challenges in the Direct Acting Antiviral Era.

Authors:  Alexander J Millman; Noele P Nelson; Claudia Vellozzi
Journal:  Curr Epidemiol Rep       Date:  2017-04-20

7.  Cohort Contributions to Race- and Gender-Specific Trends in the Incidence of Hepatocellular Carcinoma in the USA.

Authors:  Eliza W Beal; Dmitry Tumin; Ali Kabir; Dimitrios Moris; Xu-Feng Zhang; Jeffery Chakedis; Kenneth Washburn; Sylvester Black; Carl M Schmidt; Timothy M Pawlik
Journal:  World J Surg       Date:  2018-03       Impact factor: 3.352

8.  Can family physicians have a role in eradication of hepatitis c infection?

Authors:  Ahmet Rıza Şahin; Ayşegül Erdoğan; Kadir Gisi; Murat İspiroğlu; Selma Ateş; Ramazan Azim Okyay; Selçuk Nazik; Bülent Kantarçeken
Journal:  Turk J Gastroenterol       Date:  2020-05       Impact factor: 1.852

9.  The Ethics of Precision Rationing: Human Genetics and the Need for Debate on Stratifying Access to Medication.

Authors:  Alexis Walker; Angie Boyce; Priya Duggal; Chloe L Thio; Gail Geller
Journal:  Public Health Genomics       Date:  2020-06-09       Impact factor: 2.000

10.  Increasing Access to Hepatitis C Virus Medications: A Program Model Using Patient Navigators and Specialty Pharmacy to Obtain Prior Authorization Approval.

Authors:  Trang M Vu; Wilma Toribio; Farah Riazi; Genesis Ciprian; Nathalia Gibbs; Martha Giardina; Jocelyn A Camacho; Korin Parrella; Joy Cambe; Catherine Amory; Rachel Chasan; Keith M Sigel; Jeffrey J Weiss
Journal:  J Manag Care Spec Pharm       Date:  2018-04
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