| Literature DB >> 27421661 |
Aye Sandar Zaw1, Shashidhar Bangalore Kantharajanna1, Naresh Kumar2.
Abstract
Oncologic surgery is sometimes associated with substantial blood loss, and principles of patient blood management can be applied in the perioperative care of these patients. Although autologous salvaged blood is an option for perioperative blood conservation, it is often not used in oncologic surgery over concern of reinfusing tumor cells and thereby causing tumor dissemination. We reviewed the literature regarding safety and effectiveness of salvaged blood in oncologic surgery. Salvaged blood seems to be comparable to allogeneic blood in terms of safety. Because patients with primary or metastatic cancer are known to have circulating tumor cells in the absence of surgery, the concern of reinfusing malignant cells from the salvaged blood may be overstated. Reinfusion of salvaged blood has not been found to promote tumor dissemination or distant metastases. When used in patients with substantial blood loss, salvaged blood can be cost-effective. Intraoperative salvaged blood may be a useful adjunct to allogeneic blood resources.Entities:
Keywords: Circulating tumor cells; Metastasis; Oncologic surgery; Primary cancer; Salvaged blood; Tumor cells
Mesh:
Year: 2016 PMID: 27421661 DOI: 10.1016/j.tmrv.2016.06.003
Source DB: PubMed Journal: Transfus Med Rev ISSN: 0887-7963