Literature DB >> 27421661

Is Autologous Salvaged Blood a Viable Option for Patient Blood Management in Oncologic Surgery?

Aye Sandar Zaw1, Shashidhar Bangalore Kantharajanna1, Naresh Kumar2.   

Abstract

Oncologic surgery is sometimes associated with substantial blood loss, and principles of patient blood management can be applied in the perioperative care of these patients. Although autologous salvaged blood is an option for perioperative blood conservation, it is often not used in oncologic surgery over concern of reinfusing tumor cells and thereby causing tumor dissemination. We reviewed the literature regarding safety and effectiveness of salvaged blood in oncologic surgery. Salvaged blood seems to be comparable to allogeneic blood in terms of safety. Because patients with primary or metastatic cancer are known to have circulating tumor cells in the absence of surgery, the concern of reinfusing malignant cells from the salvaged blood may be overstated. Reinfusion of salvaged blood has not been found to promote tumor dissemination or distant metastases. When used in patients with substantial blood loss, salvaged blood can be cost-effective. Intraoperative salvaged blood may be a useful adjunct to allogeneic blood resources.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Circulating tumor cells; Metastasis; Oncologic surgery; Primary cancer; Salvaged blood; Tumor cells

Mesh:

Year:  2016        PMID: 27421661     DOI: 10.1016/j.tmrv.2016.06.003

Source DB:  PubMed          Journal:  Transfus Med Rev        ISSN: 0887-7963


  6 in total

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Authors:  Lyla A Youssef; Steven L Spitalnik
Journal:  Curr Opin Hematol       Date:  2017-11       Impact factor: 3.284

2.  Current Status of the Use of Salvaged Blood in Metastatic Spine Tumour Surgery.

Authors:  Naresh Kumar; Nivetha Ravikumar; Joel Yong Hao Tan; Kutbuddin Akbary; Ravish Shammi Patel; Rajesh Kannan
Journal:  Neurospine       Date:  2018-08-03

3.  Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis.

Authors:  Wei-Wei Wu; Wei-Yi Zhang; Wei-Han Zhang; Lei Yang; Xiao-Qian Deng; Meng-Chan Ou; Yao-Xin Yang; Hai-Bei Liu; Tao Zhu
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

Review 4.  Perioperative Management of Complex Hepatectomy for Colorectal Liver Metastases: The Alliance between the Surgeon and the Anesthetist.

Authors:  Enrico Giustiniano; Fulvio Nisi; Laura Rocchi; Paola C Zito; Nadia Ruggieri; Matteo M Cimino; Guido Torzilli; Maurizio Cecconi
Journal:  Cancers (Basel)       Date:  2021-05-03       Impact factor: 6.639

5.  Trial of intraoperative cell salvage versus transfusion in ovarian cancer (TIC TOC): protocol for a randomised controlled feasibility study.

Authors:  Khadra Galaal; Alberto Lopes; Colin Pritchard; Andrew Barton; Jennifer Wingham; Elsa M R Marques; John Faulds; Joanne Palmer; Patricia Jane Vickery; Catherine Ralph; Nicole Ferreira; Paul Ewings
Journal:  BMJ Open       Date:  2018-11-01       Impact factor: 2.692

6.  Impact of intraoperative allogenic and autologous transfusion on immune function and prognosis in patients with hepatocellular carcinoma.

Authors:  Youwei Gong; Yonglian Tang; Yinghong Xue; Ling Chen
Journal:  Medicine (Baltimore)       Date:  2020-10-09       Impact factor: 1.817

  6 in total

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