Literature DB >> 27421583

The Interaction of Obesity and Metabolic Syndrome in Determining Risk of Complication Following Total Joint Arthroplasty.

Adam I Edelstein1, Linda I Suleiman1, Andrew P Alvarez2, Ryan M Sacotte2, Charles D Qin2, Matthew D Beal1, David W Manning1.   

Abstract

BACKGROUND: The arthroplasty population is increasingly comorbid, and current quality improvement initiatives demand accurate risk stratification. Metabolic syndrome (MetS) has been identified as a risk factor for adverse events after arthroplasty; however, its interaction with obesity in contributing to risk is unclear.
METHODS: A retrospective analysis of all Medicare patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA) at a single institution from 2009 to 2013 investigated the interaction between MetS, body mass index (BMI), and risk for Centers for Medicare and Medicaid Services (CMS)-reportable complications, readmission, and discharge disposition.
RESULTS: A total of 1462 patients (942 TKA, 538 THA) were included, of which 16.2% had MetS. Regression analysis found that MetS was significantly related to risk of CMS complications (odds ratio [OR] = 1.96, 95% confidence interval [CI] 1.16-3.31, P = .012) and nonhome discharge (OR = 1.78, 95% CI 1.39-2.27, P < .001), but not readmission (OR = 1.23, 95% CI 0.7-2.18, P = .485). Within the MetS cohort, increasing BMI was not associated with increasing complications (P = .726) or readmissions (P = .206) but was associated with nonhome discharge (OR = 1.191 per unit increase in BMI, 95% CI 1.038-1.246, P = .001).
CONCLUSION: MetS increases risk for CMS-reportable complications and nonhome discharge disposition after THA and TKA regardless of BMI. Obesity is of less value than MetS in assessing overall risk for complication after THA and TKA.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  BMI; complications; metabolic syndrome; obesity

Mesh:

Year:  2016        PMID: 27421583     DOI: 10.1016/j.arth.2016.05.016

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  5 in total

1.  Metabolic Syndrome (MetS), Systemic Inflammatory Response Syndrome (SIRS), and Frailty: Is There any Room for Good Outcome in the Elderly Undergoing Emergency Surgery?

Authors:  Pietro Fransvea; Gianluca Costa; Luca Lepre; Gabriella Teresa Capolupo; Filippo Carannante; Caterina Puccioni; Alessandro Costa; Antonio La Greca; Francesco Giovinazzo; Gabriele Sganga
Journal:  Front Surg       Date:  2022-06-15

2.  Do In-Hospital Rothman Index Scores Predict Postdischarge Adverse Events and Discharge Location After Total Knee Arthroplasty?

Authors:  Andrew D Kleven; Austin H Middleton; Ziynet Nesibe Kesimoglu; Isaac C Slagel; Ashley E Creager; Ryan Hanson; Serdar Bozdag; Adam I Edelstein
Journal:  J Arthroplasty       Date:  2021-12-22       Impact factor: 4.757

3.  Association of Social Behaviors With Community Discharge in Patients with Total Hip and Knee Replacement.

Authors:  Kevin T Pritchard; Ickpyo Hong; James S Goodwin; Jordan R Westra; Yong-Fang Kuo; Kenneth J Ottenbacher
Journal:  J Am Med Dir Assoc       Date:  2020-10-09       Impact factor: 7.802

Review 4.  Patients with metabolic syndrome have a greater rate of complications after arthroplasty: A systematic review and meta-analysis.

Authors:  Cui Guofeng; Yue Chen; Wei Rong; Liu Ruiyu; Wang Kunzheng
Journal:  Bone Joint Res       Date:  2020-05-16       Impact factor: 5.853

5.  Association between metabolic syndrome and venous thromboembolism after total joint arthroplasty: a meta-analysis of cohort studies.

Authors:  Yipei Yang; Ziyue Li; Haifeng Liang; Jing Tian
Journal:  J Orthop Surg Res       Date:  2020-11-30       Impact factor: 2.359

  5 in total

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