Literature DB >> 2742046

Local recurrence after sphincter-saving resection for rectal adenocarcinoma.

J Warneke1, N J Petrelli, L Herrera.   

Abstract

Local pelvic-perineal recurrences were evaluated in 40 patients who underwent a sphincter-saving resection for rectal adenocarcinoma at Roswell Park Memorial Institute. The length of follow-up was at least 5 years or until death in all but one patient. There were 24 women and 16 men with a median age of 63 years. In 31 patients, the resection was considered to be curative and was considered palliative in the remaining 9 patients. Seven of the 31 patients (23 percent) developed a local recurrence. Two of the seven local recurrences had further resection for curative intent, with one person alive at 88 months. Margins of resection were available in 27 patients. Local recurrence occurred in 4 of 8 patients with distal margins of resection less than 2 cm and in 3 of 19 patients with margins greater than 2 cm. When the lesion was less than 10 cm from the anal verge, local recurrence was more likely to occur than at margins above this level.

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Mesh:

Year:  1989        PMID: 2742046     DOI: 10.1016/0002-9610(89)90302-4

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  6 in total

Review 1.  Adequate distal margin of resection for adenocarcinoma of the rectum.

Authors:  R K Phillips
Journal:  World J Surg       Date:  1992 May-Jun       Impact factor: 3.352

Review 2.  Lateral margins of resection in adenocarcinoma of the rectum.

Authors:  B G Wolff
Journal:  World J Surg       Date:  1992 May-Jun       Impact factor: 3.352

3.  Transanal endoscopic microsurgical excision of rectal tumors: indications and results.

Authors:  N Demartines; M O von Flüe; F H Harder
Journal:  World J Surg       Date:  2001-07       Impact factor: 3.352

4.  Low anterior resection versus abdominoperineal excision: a comparison of local recurrence after curative surgery for "very low" rectal cancer.

Authors:  D Tuscano; M Catarci; A Saputelli; F Gaj; F Gossetti; S Guadagni; P Negro; M Carboni
Journal:  Surg Today       Date:  1992       Impact factor: 2.549

5.  Sustained release chemotherapeutic microspheres provide superior efficacy over systemic therapy and local bolus infusions.

Authors:  Dwaine F Emerich; Pamela Snodgrass; Denise Lafreniere; Reginald L Dean; Heather Salzberg; Joanne Marsh; Brigido Perdomo; Mahin Arastu; Shelley R Winn; Raymond T Bartus
Journal:  Pharm Res       Date:  2002-07       Impact factor: 4.200

6.  Induction of VX2 para-renal carcinoma in rabbits: generation of animal model for loco-regional treatments of solid tumors.

Authors:  Sabrina Bimonte; Maddalena Leongito; Mauro Piccirillo; Maria Luisa Tamma; Marianna Vallifuoco; Adele Bracco; Antonio Mancini; Daniele Di Napoli; Sigismondo Castaldo; Santolo Cozzolino; Francesca Iacobellis; Roberto Grassi; Vincenza Granata; Secondo Lastoria; Steven Curley; Francesco Izzo
Journal:  Infect Agent Cancer       Date:  2016-12-01       Impact factor: 2.965

  6 in total

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